Results 31 to 40 of about 7,196 (208)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Investigations on particle dynamics in a high intensity heavy ion linac for inertial fusion [PDF]

open access: yes, 2005
Die Physik intensiver Ionenstrahlen wird zur Zeit für verschiedene neue Hochstrom- und Hochenergie-Beschleunigeranlagen untersucht. Ein kritischer Punkt ist dabei die Minimierung der Strahlverluste, um die Aktivierung der Beschleunigerstruktur zu ...
Parisi, Giovanni
core  

National Energy Research Scientific Computing Center (NERSC): Advancing the frontiers of computational science and technology

open access: yes, 1996
National Energy Research Scientific Computing Center (NERSC) provides researchers with high-performance computing tools to tackle science`s biggest and most challenging problems.
Hules, J.
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

GL(1) charged states in twistor string theory

open access: yes, 2005
We discuss the appearance of the GL(1) charged physical operators in the twistor string theory. These operators are shown to be BRST-invariant and non-trivial and some of their correlators and conformal β-functions are computed.
Polyakov D.
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The phase diagram of neutral quark matter [PDF]

open access: yes, 2007
In this thesis, I study the phase diagram of dense, locally neutral three-flavor quark matter as a function of the strange quark mass, the quark chemical potential, and the temperature, employing a general nine-parameter ansatz for the gap matrix.
Rüster, Stefan Bernhard
core  

How structural factors influence the performance of copper(I) bis(diimine) based DSCs [PDF]

open access: yes, 2014
This PhD thesis is based on the synthesis of new homoleptic copper(I) complexes and their applications in dye-sensitized-solar-cells (DSCs). Chapter I: Is an evaluation of the anchoring ligands effect upon device performance containing ancillary ...
Brauchli, Sven Yves
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Non-Supersymmetric Charged Domain Walls

open access: yes, 2006
We present general non-supersymmtric domain wall solutions with non-trivial scalar and gauge fields for gauged five-dimensional N=2 supergravity coupled to abelian vector ...
Gutowski, JB   +3 more
core   +1 more source

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