Results 101 to 110 of about 2,258,898 (310)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Mountain Broadcast and Prairie Recorder: Devoted to the American tradition in folk music.
The Mountain Broadcast and Prairie Recorder was dedicated to information about folk and country songs and singers in the United States. These issues are from the collection of Floy Case, a pioneering music journalist who wrote many articles for this ...
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Jesus Name Tradition services home movie, 1973
Video recording of three separate Jesus Name Tradition services. The recording features members, including Johnny Holbrook and Larry Eldridge, handling serpents, drinking strychnine, and dancing with fire.
Vance, Mary
core +1 more source
Implementing Name Authority Control into Institutional Repositories: A Staged Approach [PDF]
This presentation discusses name authority for institutional repositories. It gives an overview of some major initiatives in name authority and outlines the staged approach taken by the UNT ...
Phillips, Mark Edward
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On the Poetic Dispute between Paul Celan and Johannes Bobrowski
The main purpose of this work is to explore the experience of confronting guilt ‘after Auschwitz’ in the creative dialogue between two significant poets of the twentieth century — Paul Celan and Johannes Bobrowski.
Gilmanov V. Kh., Kotilenkova A.A.
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Famous smoke stack with Seabrook name in brick
The famous smoke stack with Seabrook name in brick. At one time, this was known as the tallest building in the area and was built by the John B. Kelly Construction Company of Philadelphia. Picture taken in July 1979, the same month and year in which the
core +1 more source
As in many other areas settled by Slavs, the territory which is and was called Slavonia, was named in the early Middle Ages after its inhabitants, the Slavs, Slověne. The root *Slověn- in various dialects appears as Slovin-, Sloven- + -ec, -ac.
Alemko Gluhak
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