Results 111 to 120 of about 2,624,449 (251)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Precedent in Poetry as a Strategy of Linguistic Influence and Manipulation
RUDN Journal of Language Studies, Semiotics and SemanticsThe precedent in poetry is a strategy of linguistic influence and manipulation to identify its mechanisms and functions in shaping reader perception and emotional response. Precedent phenomena in poetry are considered as a powerful, but often hidden tool
Anna V. Okulich-Kazarina +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Shakespeare Name and Place Dictionary
Entries provide the likely sources for a name; describe historical and mythological backgrounds; examine Shakespeare's presentation of a character or place; and suggest various interpretations of a name.
Davis, J. Madison. +1 more
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North Carolina Presidential, Senatorial, Gubernatorial, and Row Office Election Results by County: 2002 ...
Name, A
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
This thesis project explores the intersections of contemporary art and societal tensions through a large-scale, three-tiered altar installation titled In The Name Of.
Palpa, Daniel
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The Mountain Broadcast and Prairie Recorder: Devoted to the American tradition in folk music.
, 1947 The Mountain Broadcast and Prairie Recorder was dedicated to information about folk and country songs and singers in the United States. These issues are from the collection of Floy Case, a pioneering music journalist who wrote many articles for this ...
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source