Results 81 to 90 of about 3,607 (224)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Richard Austin Letter : February 4, 1862 [PDF]
Richard makes note of the many rain and snow storms they experienced in the past three weeks. He reassures Eliza that he attends church often and has given his name to the local Methodist Episcopal Church.
Beers, Josiah L. +1 more
core
, 2004 Folkloristic and anthropological studies presenting a festival and the way of celebration are usually concerned with the festivals of religious communities. Religion and celebration are in a way closely connected.
Gulyás Gáborné Kiss Bernadett
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Chinese community marchers in Potlatch parade on Second Avenue, Seattle, 1938 [PDF]
, 1938 Seattle's Potlatch of Progress opened July 28, 1938. During its four sunny days of events, Seattleites and visitors enjoyed several parades, a Native American canoe race, a swim carnival, horseracing, fishing contests, fireworks at Green Lake and the ...
Staff Photographer Seattle Post-Intelligencer
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Velvet tobacco parade float in Golden Potlatch parade, Seattle, ca. 1913 [PDF]
, 1913 The Tilikums of Elttaes were a fraternal, civic organization composed primarily of influential white Seattle area businessmen, who used Native American imagery to promote tourism and the economic development of the city.
Nowell, Frank H.
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Decorated Buick in Golden Potlatch parade, Seattle, ca. 1913 [PDF]
, 1913 The Tilikums of Elttaes were a fraternal, civic organization composed primarily of influential white Seattle area businessmen, who used Native American imagery to promote tourism and the economic development of the city.
Nowell, Frank H.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source