Results 51 to 60 of about 236,995 (259)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
IEEE Access, 2018 Internet traffic volume is continuing to increase rapidly. Named data networking (NDN) has been introduced to support this Internet traffic growth through caching contents close to consumers.
Anselme Ndikumana +5 more
doaj +1 more source
Results in Engineering, 2022 Technology and applications of Internet of Things (IOT) is expanding. Large number of smart devices with networking capabilities, often called endpoints are part of IOT networks.
H.S. Shrisha, Uma Boregowda
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Pipe failure prediction of wastewater network using genetic programming: Proposing three approaches
Ain Shams Engineering Journal, 2023 Finding critical points of the wastewater network by rebuilding the infrastructure is cheaper than repairing it after occurring failure. This task can be done by using predictive approaches.
Pegah Hoseingholi, Ramtin Moeini
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
DENA: An Intelligent Content Discovery System Used in Named Data Networking
IEEE Access, 2016 Named data networking (NDN) aims at efficient content delivery and reducing the redundancy of data transmission. In NDN, one of the most important issues is how to utilize the cached contents to reduce the user's response delay and improve the ...
Hengyang Zhang +4 more
doaj +1 more source
Named Data Networking: A Survey on Routing Strategies
IEEE Access, 2022 As the Internet grows in popularity, data become an increasingly crucial component. People now care more about the data than the data location. Named data network (NDN) takes this concept and pairs it with the idea of making data a core component rather ...
Farhan Ahmed Karim +4 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source