Results 61 to 70 of about 27,584,206 (303)

The 'named person': surveillance and the wellbeing of children and young people in Scotland. [PDF]

open access: yes, 2015
The Scottish Parliament’s ‘Children and Young People’ Bill has extended statutory responsibilities for the welfare of children to include their well-being.
Stoddart, Eric
core   +2 more sources

Comparative Analysis of Popularity Aware Caching Strategies in Wireless-Based NDN Based IoT Environment

open access: yesIEEE Access
The fundamental objective of the Internet of Things (IoT) and Named Data Networking (NDN) architectures is to facilitate the provision of communication services.
Yahui Meng   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

PopNetCod: A Popularity-based Caching Policy for Network Coding-enabled Named Data Networking [PDF]

open access: yes, 2018
In this paper, we propose PopNetCod, a popularity-based caching policy for network coding enabled Named Data Networking. PopNetCod is a distributed caching policy, in which each router measures the local popularity of the content objects by analyzing the
Bourtsoulatze, Eirina   +12 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Joint Incentive Mechanism for Paid Content Caching and Price Based Cache Replacement Policy in Named Data Networking

open access: yesIEEE Access, 2018
Internet traffic volume is continuing to increase rapidly. Named data networking (NDN) has been introduced to support this Internet traffic growth through caching contents close to consumers.
Anselme Ndikumana   +5 more
doaj   +1 more source

An energy efficient and scalable endpoint linked green content caching for Named Data Network based Internet of Things

open access: yesResults in Engineering, 2022
Technology and applications of Internet of Things (IOT) is expanding. Large number of smart devices with networking capabilities, often called endpoints are part of IOT networks.
H.S. Shrisha, Uma Boregowda
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Pipe failure prediction of wastewater network using genetic programming: Proposing three approaches

open access: yesAin Shams Engineering Journal, 2023
Finding critical points of the wastewater network by rebuilding the infrastructure is cheaper than repairing it after occurring failure. This task can be done by using predictive approaches.
Pegah Hoseingholi, Ramtin Moeini
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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