Results 81 to 90 of about 223,808 (279)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Software-Defined Named Data Networking in Literature: A Review

Future Internet
This paper presents an in-depth review of software-defined named data networking (SD-NDN), a transformative approach in network architectures poised to deliver substantial benefits.
Albatool Alhawas, Abdelfettah Belghith
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

An Indoor Positioning and Navigation System Using Named Data Networking

IEEE Access, 2020
Named data networking (NDN) is a new and promising Internet architecture, which aims to replace the current transmission control protocol/Internet protocol (TCP/IP)-based Internet. The NDN internet architecture has introduced several benefits in numerous
Sifat Ut Taki, Amitabha Chakrabarty, Md. Jalil Piran, Quoc-Viet Pham, Doug Young Suh   +4 more
doaj   +1 more source

Content-Centric Networking at Internet Scale through The Integration of Name Resolution and Routing

, 2016
We introduce CCN-RAMP (Routing to Anchors Matching Prefixes), a new approach to content-centric networking. CCN-RAMP offers all the advantages of the Named Data Networking (NDN) and Content-Centric Networking (CCNx) but eliminates the need to either use ...
Afanasyev A., Afanasyev A., Gritter M., Raju J., Wahlisch M., Wang Y., Xylomenos G., Yuan H.   +7 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Challenges and Opportunities of Named Data Networking in Vehicle-To-Everything Communication: A Review

Information, 2018
Many car manufacturers have recently proposed to release autonomous self-driving cars within the next few years. Information gathered by sensors (e.g., cameras, GPS, lidar, radar, ultrasonic) enable cars to drive autonomously on roads.
Benjamin Rainer, Stefan Petscharnig
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

BigFCM: Fast, Precise and Scalable FCM on Hadoop

, 2016
Clustering plays an important role in mining big data both as a modeling technique and a preprocessing step in many data mining process implementations.
Ghadiri, Nasser, Ghaffari, Meysam, Nikbakht, Mohammad Amin   +2 more
core   +1 more source