Results 171 to 180 of about 19,464 (251)

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, EarlyView.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Optimisation of verapamil hydrochloride loaded polyhydroxyalkanoate nano and microparticles using response surface methodology. [PDF]

Sci Rep
Ramachandran S, Prakash P, Raman S, Dheyab MA, Sudesh K, Moses EJ, Parumasivam T.   +6 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Novel Antimicrobial-Decorated Polyelectrolytes as Versatile Building Blocks for Multifunctional Hydrogel Nano- and Microparticles. [PDF]

ACS Omega
Szczęsna-Górniak W, Lamch Ł, Surowiak A, Zboińska E, Szyk-Warszyńska L, Bartman M, Warszyński P, Wilk KA.   +7 more
europepmc   +1 more source

Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke

Advanced Healthcare Materials, Volume 15, Issue 25, 3 July 2026.
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan, Damien Levard, Eloïse Lemarchand, Amal Boublay, Charly Helaine, Jolan Malherbe, Mikaël Naveau, Didier Goux, Igor Khalin, Ankita Talukdar, Cheun Pelleter, Charlène Jacqmarcq, Erwan Baudron, Isabelle Bardou, Sara Martinez de Lizarrondo, Maxime Gauberti, Denis Vivien, Antoine Philippe Fournier   +17 more
wiley   +1 more source

Protein Adsorption on Nano- and Microparticles: Dependence on Morphological and Physicochemical Properties of Particles and Effect on Particle-Cell Interactions. [PDF]

Nanomaterials (Basel)
Gerasimovich E, Karaulov A, Nabiev I, Sukhanova A.   +3 more
europepmc   +1 more source

A Review of Breath Sensing for Disease Monitoring and Diagnosis: Breathomics, Artificial Intelligence, and Nanomaterials for the Future of Medicine

Advanced Sensor Research, Volume 5, Issue 7, July 2026.
Breathomics is established as a non‐invasive diagnostic strategy by combining volatile organic compound biomarkers, nanomaterial‐based sensor arrays, and AI‐driven classification. Key diseases, sensing materials, and analytical challenges are critically compared, revealing how portable, data‐enabled breath platforms are moving toward clinically useful ...
Anesu Nyabadza, Mayur Makhesana, Suman Chatterjee, Dermot Brabazon   +3 more
wiley   +1 more source

Lung-Targeted Itraconazole Delivery Using PVA-Based Nano-in-Microparticles for Improved Treatment of Pulmonary Aspergillosis. [PDF]

Int J Nanomedicine
Jeong JH, Lee HS, Choi JC, Kang JH, Kim DW, Park CS, Park CW.   +6 more
europepmc   +1 more source

On the shape-dependent propulsion of nano- and microparticles by traveling ultrasound waves. [PDF]

Nanoscale Adv, 2020
Voß J, Wittkowski R.
europepmc   +1 more source

Microneedle‐Assisted Systems for the Delivery of Proteolysis Targeting Chimeras (PROTACs)

Advanced Therapeutics, Volume 9, Issue 7, July 2026.
The advent of Microneedle arrays has conferred a minimally invasive transdermal platform for the delivery of targeted protein‐degradation agents, especially Proteolysis‐Targeting Chimeras (PROTACs). By overcoming solubility and bioavailability barriers, this approach enhances localized cancer therapy.
Pooja Tiwary, Krishil Oswal, Aishwarya Shirke, Heena Maithania, Ryan Varghese, Lalit Kumar Vora   +5 more
wiley   +1 more source