Results 41 to 50 of about 457,382 (266)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Field experiment pitting magnetite nanoparticles against microparticles: Effect of size in the rehabilitation of metalcontaminated soil

Revista Brasileira de Ciência do Solo, 2023
A significant portion of the current knowledge regarding the use of iron nanoparticles for remediating metal-contaminated soils is derived from laboratory experiments, leaving several unanswered questions.
Ivan A. Smorkalov, Evgenii L. Vorobeichik, Artur A. Dzeranov, Denis A. Pankratov, Elvira A. Dovletyarova, Carolina Yáñez, Alexander Neaman   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Mechanical Properties of Nano-TiO₂-Modified Concrete Under Freeze–Thaw Environment

Nanomaterials
This study investigated the freeze–thaw resistance of ordinary and nano-TiO2-modified concrete (NTC) based on mass loss, ultrasonic velocity, compressive strength, and fracture toughness.
Chao Xu, Lin Deng, Dingtao Yang
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

THE POSSIBILITY OF USING NANOFERTILIZERS TO RAISE THE EFFICIENCY OF VEGETABLE CROPS PRODUCTIVITY, IMPROVE THE QUALITY AND REDUCE THE DAMAGE OF BIOLOGICAL STRESSES (REVIEW ARTICLE) [PDF]

Mesopotamia Journal of Agriculture, 2020
Several methods were used to increase productivity and quality of the product for vegetable crops and prolong their presence in the markets, including the treatment of various vegetable crops with industrial growth regulators and mineral fertilizers ...
Fathel Ibraheem
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Preparation of aluminum sulfate nanoparticles prepared by the green method and study of their effect on a poly(vinyl chloride) surface [PDF]

مجلة جامعة الانبار للعلوم الصرفة
In this study, aluminum sulfate nanoparticles (ASNPs) were prepared using Ziziphus spina leaf extract. Poly(vinyl chloride) (PVC) films with a thickness of 50 ± 5 µm were then prepared by the casting method after adding the nanomaterial at ...
Namaa Attallah, Hameed Ali, Muthana Sirhan   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source