Results 121 to 130 of about 12,558 (240)

Oral creatine-modified selenium-based hyaluronic acid nanogel mediated mitochondrial energy recovery to drive the treatment of inflammatory bowel disease

Journal of Nanobiotechnology
The damnification of mitochondrion is often considered to be an important culprit of inflammatory bowel disease (IBD), however, there are fewer reports of mechanisms of mitochondria-mediated IBD treatment.
Manxiu Huai, Mingliang Pei, Jie Chen, Xiaoyan Duan, Yun Zhu, Fan Yang, Wensong Ge   +6 more
doaj   +1 more source

Development of Quercetin Micellar Nanogel: Formulation, Characterization, and In Vitro Cytotoxocity Study

Micro
Quercetin, a flavonoid, has well-proven cytotoxicity potential, but its therapeutic efficacy is hampered by hydrophobicity, stability issues, and lower bioavailability.
Harshad S. Kapare, Sunil Kanadje, Prabhanjan Giram, Aditi Patil, Ritesh P. Bhole   +4 more
doaj   +1 more source

Maleimide-bearing nanogels as novel mucoadhesive materials for drug delivery [PDF]

, 2016
Novel maleimide-functionalised nanogels have been synthesised via the polymerisation of 2,5-dimethylfuran-protected 3-maleimidoethyl butylacrylate in the presence of presynthesised poly(N-vinylpyrrolidone) (PVP) nanogel scaffolds using surfactant-free ...
Andrews, Bernkop-Schnurch, Bernkop-Schnürch, Boddupalli, Chacko, Cook, Davidovich-Pinhas, Davidovich-Pinhas, Ellman, Fontaine, Hasegawa, Hayashi, Irmukhametova, Kao, Khutoryanskiy, Khutoryanskiy, Li, Li, Lowe, Ludwig, Mantovani, Maya, Molina, Morales, Nair, Northrop, Peppas, Prosperi-Porta, Schmitz, Shaikh, Singhvi, Sosnik, Storha, Syrett, Valenta, Wagh, Xu, Yang   +37 more
core   +1 more source

A Comprehensive Review of Adsorbents for Rare Earth Separation: Design, Synthesis, Adsorption Performance, and Mechanisms

Rare Metals, EarlyView.
ABSTRACT Rare earth elements (REEs) play an irreplaceable role in modern technology and industry. However, due to the highly similar physicochemical properties among REEs, their separation remains a significant challenge. Additionally, REEs often exist in low‐concentration solutions, making efficient REE recovery an urgent task.
Miao‐Miao Huang, Jun Tan, Liu‐Yin Xia, Kai Han, Hong‐Yan Cai, Xin Ma, Shuai Wang   +6 more
wiley   +1 more source

Anticancer potential of thiocolchicoside and lauric acid loaded chitosan nanogel against oral cancer cell lines: a comprehensive study

Scientific Reports
The present study explored the anticancer activity of a Chitosan-based nanogel incorporating thiocolchicoside and lauric acid (CTL) against oral cancer cell lines (KB-1). Cell viability, AO/EtBr dual staining and Cell cycle analysis were done to evaluate
Ameena Mustafa, Meignana Arumugham Indiran, Karthikeyan Ramalingam, Elumalai Perumal, Rajeshkumar Shanmugham, Mohmed Isaqali Karobari   +5 more
doaj   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

Rare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang, Jiatong Lin, Yi Peng, Zehua Wu, Yingying Liu, Wei Duan, Qiaolin Wei, Jia‐Wei Shen, Jiang‐Xing Chen, Yong Guo   +9 more
wiley   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Synthesis of polymeric nanogel via irradiation of inverse micelles technique [PDF]

, 2012
Covalently cross-linked nanogels were prepared via irradiation of inverse micelles that had been prepared from radiation crosslinkable polymer, water, oil and surfactant.
Hamzah, Yusof, Mat Isa, Naurah, Wan Yunus, Wan Md Zin   +2 more
core  

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source