Results 191 to 200 of about 9,117 (234)
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2020
Magnetic nanogels represent a cutting edge of magnetic soft matter research due to their numerous potential applications. Here, using Langevin dynamics simulations, was analysed the influence of magnetic nanogel concentration and embedded magnetic particle interactions on the self-assembly of magnetic nanogels at zero field.
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Magnetic nanogels represent a cutting edge of magnetic soft matter research due to their numerous potential applications. Here, using Langevin dynamics simulations, was analysed the influence of magnetic nanogel concentration and embedded magnetic particle interactions on the self-assembly of magnetic nanogels at zero field.
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Functionalizable and Ultrastable Zwitterionic Nanogels
Langmuir, 2010Multifunctional biomimetic nanogels based on zwitterionic poly(carboxybetaine methacrylate) (pCBMA) were synthesized by inverse microemulsion free-radical polymerization. pCBMA nanogels exhibited excellent stability in 100% fetal bovine serum. Dextran labeled with fluorescein isothiocyanate (FITC-dextran) was encapsulated in nanogels as a model drug ...
Gang, Cheng +6 more
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Nanogels for delivery, imaging and therapy
WIREs Nanomedicine and Nanobiotechnology, 2015Nanogels are hydrogels having size in nanoregime, which is composed of cross‐linked polymer networks. The advantages of nanogels include stimuli‐responsive nature, easy drug loading, and higher drug‐loading capacity, physical stability, versatility in design, stability of entrapped drug, and controlled release of the anti‐inflammatory, antimicrobial ...
Sivaram, Amal J. +4 more
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Multifunctional Nanogels for siRNA Delivery
Accounts of Chemical Research, 2011The application of RNA interference to treat disease is an important yet challenging concept in modern medicine. In particular, small interfering RNA (siRNA) have shown tremendous promise in the treatment of cancer. However, siRNA show poor pharmacological properties, which presents a major hurdle for effective disease treatment especially through ...
Michael H, Smith, L Andrew, Lyon
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Molecular Fundamentals of Enzyme Nanogels
The Journal of Physical Chemistry B, 2008The assembly of a monomer around an enzyme as the essential step in the fabrication of enzyme nanogel by in situ polymerization was illustrated by molecular dynamics simulation and evidenced by a fluorescence resonance energy transfer spectrum, using lipase/acrylamide as a model system.
Jun, Ge +5 more
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Nanogels in The Race for Drug Delivery
Nanomedicine, 2010We are currently witnessing a rapid growth of interest in nanotech applications for medicine, most of them focused on radical improvements of current therapies and diagnostic modalities. After a real boom in the development of novel micro- and nano-sized particulate drug delivery systems (DDS) in academic laboratories and pharmaceutical companies all ...
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Nanogels for Drug Delivery: The Key Role of Nanogel–Drug Interactions
Nanogels are cross-linked colloidal particles, which can swell by absorption (uptake) of large amounts of solvent, but they do not dissolve due to the constituting structure of the polymeric network, and can be physically or chemically cross-linked.José Ramos +5 more
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Rheology of Magnetic Nanogel Suspensions
The Journal of Physical Chemistry BMagnetic nanogels (MNGs)─deformable colloidal particles composed of cross-linked polymers with embedded magnetic nanoparticles (MNPs)─facilitate remote manipulation of their rheology and internal structure through biocompatible magnetic fields. This property renders MNGs particularly promising for applications in drug delivery and hyperthermia ...
Ivan S. Novikau, Sofia S. Kantorovich
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