Results 121 to 130 of about 50,752 (264)

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Dynamic Covalent Networks of Molecular Clusters for Hard and Impact‐Resistant Glass with Feasible Processability

Advanced Science, EarlyView.
Molecular granular material glass is fabricated by crosslinking sub‐nm POSS clusters with dynamic borate ester bonding while the materials combine high transparency, modulus, and hardness with superior impact resistance and (re)processability, offering a promising strategy for creating robust yet highly processable organic glasses.
Haiyan Xiao, Jia‐Fu Yin, Linjie Lan, Wei Liu‐Fu, Panchao Yin   +4 more
wiley   +1 more source

Interfacially Reinforced Crosslinked Binder with Structural Integrity for Stable Micro‐Sized Silicon Anodes in All‐solid‐state Batteries

Advanced Science, EarlyView.
ABSTRACT All‐solid‐state batteries (ASSBs) have attracted considerable attention as next‐generation energy storage systems owing to their high energy density and safety. However, their performance is critically limited by insufficient solid–solid interfacial contact and severe chemomechanical degradation, particularly for micro‐sized silicon (µSi ...
Chanho Lee, Yuri Nam, Incheol Jeong, Seo Eun Lee, Taewook Kim, Jinhyung Kim, Wooseup Jo, Moonsu Yoon, Jongkyeong Lim, Seho Sun, Junghyun Choi, Chan Ho Park, Dongsoo Lee   +12 more
wiley   +1 more source

Study on the Effects of Cryogenic Treatment on WC-Co Cemented Carbide at Different Scales Using an Indentation Technique

Metals
Cemented carbide (WC-Co) combines high hardness, wear resistance, and toughness, making it ideal for tooling applications. This study investigated cryogenic treatment’s effects on the mechanical properties of samples from various suppliers prepared at ...
Suparoj Premjarunan, Karuna Tuchinda, Kaweewat Worasaen   +2 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Temperature-driven nanoscale brittle-to-ductile transition of the C15 CaAl2 Laves phase

Materials & Design
The influence of temperature on the deformation behaviour of the C15 CaAl2 Laves phase, a key constituent for enhancing the mechanical properties of Mg alloys up to service temperatures of 200 °C, remains largely unexplored.
Anwesha Kanjilal, Ali Ahmadian, Martina Freund, Pei-Ling Sun, Sandra Korte-Kerzel, Gerhard Dehm, James P. Best   +6 more
doaj   +1 more source

Molecularly Bridged Heterointerface Engineering: Designing Transparent, Wear‐Resistant, Hard yet Flexible Optoelectronic Protective Film

Advanced Science, EarlyView.
A molecular‐bridging heterogeneous interface engineering strategy is introduced to combine a polyhedral oligomeric silsesquioxane (POSS)‐based hard coating with a colorless polyimide (CPI)‐based flexible layer. The robust heterogeneous interface endows the integrated system with the superior properties of both layers and their synergistic ...
Huiyang Lu, Zihui Liu, Jianan Yuan, Yunhao Wei, Shuangfei Xiang, Qinghua Lu   +5 more
wiley   +1 more source

Effect of Increased Extrusion Ram Speed and Liquid Nitrogen Cooling on the Mechanical Properties of 6060 Aluminum Alloy

Metals
This study investigates the impact of increased extrusion ram speed—achieved by utilizing liquid nitrogen as a die cooling agent—on the mechanical properties of a 6060-aluminum alloy.
Evangelos Giarmas, Emmanouil Tzimtzimis, Konstantinos Tsongas, Apostolos Korlos, Constantine David, Dimitrios Tzetzis   +5 more
doaj   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Bamboo‐Like Whiskers‐Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type‐H Vessels and Osteoinduction

Advanced Science, EarlyView.
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng, Haibo Teng, Chuyao Xu, Jiaze He, Keting Liu, Xueying Li, Kai Zhang, Xiangdong Zhu, Xiangfeng Li, Jianguo Xu, Xingdong Zhang   +10 more
wiley   +1 more source