Measuring Melanoma Nanomechanical Properties in Relation to Metastatic Ability and Anti-Cancer Drug Treatment Using Scanning Ion Conductance Microscopy [PDF]
Cells, 2023 A cell’s mechanical properties have been linked to cancer development, motility and metastasis and are therefore an attractive target as a universal, reliable cancer marker. For example, it has been widely published that cancer cells show a lower Young’s
Emily Woodcock +6 more
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Comparing Nanomechanical Properties and Membrane Roughness Along the Aging of Human Erythrocytes [PDF]
Methods and ProtocolsErythrocyte (RBC) aging involves significant structural and nanomechanical alterations crucial to their function. This study aims to bridge the gap between analyses based on statistical morphometric parameters, e.g., membrane roughness, and those based ...
Giovanni Longo +3 more
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Nanomechanical properties of rough surfaces [PDF]
Materials Research, 2006 The nanoindentation technique allows the determination of mechanical properties at nanometric scale. Hardness (H) and elastic modulus (E) profiles are usually determined by using the Oliver-Pharr method from the load/unload curves. This approach is valid
Gelson Biscaia de Souza +3 more
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Bone Nanomechanical Properties and Relationship to Bone Turnover and Architecture in Patients With Atypical Femur Fractures: A Prospective Nested Case‐Control Study [PDF]
JBMR Plus, 2021 Atypical femur fractures (AFFs) are well‐established serious complication of long‐term bisphosphonate and denosumab therapy in patients with osteopenia or osteoporosis.
Lanny V. Griffin +7 more
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Machine learning-based approach for automated classification of cell and extracellular matrix using nanomechanical properties [PDF]
Materials Today BioFibrosis characterized by excess accumulation of extracellular matrix (ECM) due to complex cell-ECM interactions plays a pivotal role in pathogenesis. Herein, we employ the pancreatic ductal adenocarcinoma (PDAC) model to investigate dynamic alterations ...
Tanmay Kulkarni +4 more
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Nanomechanical properties of steric zipper globular structures. [PDF]
Proc Natl Acad Sci U S A, 2019 SignificanceThe increase in life expectancy has nowadays positioned neurodegenerative diseases as a leading cause of death. Neurodegeneration is related to early amyloid protein aggregation; however, in the lack of an aggregation mechanism, neurodegenerative diseases still remain neither cured nor prevented.
Lester-Zer N, Ghrayeb M, Chai L.
europepmc +4 more sources
Nanomechanical properties of neutron-irradiated concrete
Acta Polytechnica CTU ProceedingsConcrete exposed to irradiation from nuclear reactor undergoes atomic-level degradation due to the influence of neutrons, secondary gamma rays, and associated gamma heating. The radiationinduced damage decreases the mechanical properties of the concrete
Ondřej Libera +4 more
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Protein adsorption by nanomechanical mass spectrometry: Beyond the real-time molecular weighting
Frontiers in Molecular Biosciences, 2023 During past decades, enormous progress in understanding the mechanisms of the intermolecular interactions between the protein and surface at the single-molecule level has been achieved.
Ivo Stachiv, Chih-Yun Kuo, Wei Li
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Nanomechanical Properties of Phospholipid Microbubbles [PDF]
Langmuir, 2012 This study uses atomic force microscopy (AFM) force-deformation (F-Δ) curves to investigate for the first time the Young's modulus of a phospholipid microbubble (MB) ultrasound contrast agent. The stiffness of the MBs was calculated from the gradient of the F-Δ curves, and the Young's modulus of the MB shell was calculated by employing two different ...
Evelyn, Buchner Santos +4 more
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Advances in Condensed Matter Physics, 2023 Aurivillus oxide thin films with nanostructures attained much interest due to their structural stability, outstanding ferroelectric, and dielectric properties.
A. Rambabu +4 more
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