Results 41 to 50 of about 8,812 (236)
α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration [PDF]
, 2016 Lysosomal storage disorders (LSD) are caused by lysosomal dysfunction usually as a consequence of deficiency of a single enzyme required for the metabolism of macromolecules, such as lipids, glycoproteins, and mucopolysaccharides.
Bueno, María Dolores +9 more
core +1 more source
Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection
Angewandte Chemie, EarlyView.In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González +5 more
wiley +2 more sources
Hydraulic fracturing in cells and tissues: fracking meets cell biology [PDF]
, 2017 The animal body is fundamentally made of water. A small fraction of this water is freely flowing in blood and lymph, but most of it is trapped in hydrogels such as the extracellular matrix (ECM), the cytoskeleton, and chromatin.
Arroyo Balaguer, Marino +1 more
core +4 more sources
On the use of the Bingham statistical distribution in microsphere-based constitutive models for arterial tissue [PDF]
, 2010 Constitutive models for arterial tissue have been an active research field during the last years. The main micro-constituents of blood vessels are different types of cells and the extra-cellular matrix formed by an isotropic high water content ground ...
Alastrué, V. +3 more
core +2 more sources
Mundo NanoEl advenimiento de la nanomedicina representa una nueva frontera en las ciencias de la salud. La capacidad de la nanomedicina para mejorar la selectividad, eficacia y perfil de seguridad de las terapias convencionales ofrece esperanzas de abordar ...
Luz María López Marín +2 more
doaj +1 more source
Desafíos de la investigación nanomédica en México
Entreciencias: Diálogos en la Sociedad del ConocimientoObjetivo: identificar los desafíos que enfrenta la investigación en nanomedicina en México según la opinión de expertos en la materia. Diseño metodológico: se realizaron entrevistas semiestructuradas a investigadores mexicanos del área de nanomedicina.
Roberto Soto Vázquez +2 more
doaj +1 more source
Recent advances in mesoporous silica nanoparticles for antitumor therapy: our contribution [PDF]
, 2016 Since 2001, when our research group proposed for the first time MCM-41 as a drug release system, the scientific community has demonstrated a growing interest in mesoporous silica nanoparticles (MSNs) for their revolutionary potential in nanomedicine ...
Baeza García, Alejandro +3 more
core +1 more source
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
El primer Workshop de Nanomedicina reuneix més de 220 experts [PDF]
, 2012 Més de 220 investigadors experts en nanomedicina participen en el primer Workshop en Nanomedicina, organitzat en el marc del projecte UAB-CEI, a l'Hotel Campus de la ...
core
Enhanced i-Motif Stability through Consecutive 2',2'-Difluorocytidine Incorporation. [PDF]
ChemistryGemcitabine (dFdC) is a unique nucleoside containing two fluorine atoms at the 2′‐position. Using circular dichroism (CD) and nuclear magnetic resonance spectroscopy, we discovered that consecutive dFdC confer remarkable thermal and pH i‐motif stability. In particular, the molecular surface of the fully modified human vertebrate i‐motif structure shows
Domínguez A +7 more
europepmc +2 more sources