Results 51 to 60 of about 3,025 (197)
Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems
DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther +9 more
wiley +1 more source
Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy
Abstract INTRODUCTION A subset of Alzheimer's disease (AD) patients exhibits a procoagulant state that remains undiagnosed despite available treatments. We developed positron emission tomography (PET) strategies to in vivo detect cerebral microthrombi in TgCRND8 mice. METHODS PET was performed with a fibrin‐binding probe (FBP) in TgCRND8 and wild‐type
Carlos Ceron +22 more
wiley +1 more source
Sistemas auto-nanoemulsionables de liberación de fármacos en el desarrollo de medicamentos
Los Sistemas Auto-Nanoemulsionables (SNEDDS) son formulaciones farmacéuticas basadas en nanotecnología que son de gran interés para fármacos poco solubles en agua (FPSA).
Adriana Estela Hernández Tenorio +5 more
doaj +1 more source
Abstract BACKGROUND Obesity and its metabolic complications, such as insulin resistance and cognitive decline, remain a global health challenge. Green tea (Camelia sinensis) and ω‐3 polyunsaturated fatty acids (PUFAs) are recognized for their antioxidant, anti‐inflammatory, and neuroprotective properties.
Paola Finetti‐Casanova +5 more
wiley +1 more source
Rak sečnega mehurja je v svetovnem merilu 10. najpogostejši rak z izjemno visoko ponovljivostjo. Slovenska incidenca, umrljivost in prevalenca so pri tem raku v primerjavi z drugimi evropskimi državami in svetom nadpovprečne.
Daša Zupančič, Larisa Tratnjek
doaj +1 more source
ABSTRACT Purpose We aim to inform the design of new diffusion MRI (dMRI) approaches for microvasculature quantification that enhance the biological specificity of imaging towards cancer. Methods We adopted simulation‐informed modelling of the vascular dMRI signal. We synthesised signals from 1500 synthetic vascular networks, for a variety of protocols (
Anna Kira Voronova +11 more
wiley +1 more source
In vitro and in vivo effects of PTSO in colorectal cancer preclinical models, highlighting antiproliferative, pro‐apoptotic, barrier‐enhancing, antitumor, prebiotic and immunomodulatory properties. Created using BioRender. ABSTRACT Allium‐derived organosulfur compounds offer significant health benefits.
María Jesús Rodríguez‐Sojo +16 more
wiley +1 more source
Indocyanine Green Nanoparticles: Are They Compelling for Cancer Treatment?
Indocyanine green (ICG) is a Food and Drug Administration–approved near-infrared fluorescent dye, employed as an imaging agent for different clinical applications due to its attractive physicochemical properties, high sensitivity, and safety.
Marta Sevieri +7 more
doaj +1 more source
This study presents a plasmonic thermal lateral flow (ThermoLFA) biosensor for ultrasensitive, early detection of biomolecules. By combining plasmonic gold nanoprisms (AuNPrs) and near‐infrared (NIR) laser activation, it enhances signal output beyond conventional LFAs.
Carlos Cuestas Ayllón +5 more
wiley +1 more source

