Results 41 to 50 of about 3,025 (197)

Development of Betalactam‐Predictor: A Clinical Decision Tool for Delabeling Low‐Risk Betalactam Allergy Patients. Initial Validation in Penicillin Allergy

open access: yesAllergy, EarlyView.
BL‐Predictor has emerged as a new tool for delabeling penicillin allergy. External validation has shown a specificity of 93% for detecting low‐risk patients. This score could potentially reduce diagnostic costs and the negative consequences associated with incorrect antibiotic allergy labels.
Marina Labella   +14 more
wiley   +1 more source

Uso da nanotecnologia no reparo das lesões traumáticas de nervos

open access: yesBrazilian Neurosurgery, 2007
A nanotecnologia tem permitido avanços revolucionários nos últimos anos em diversas áreas da Ciência, incluindo a medicina, onde o impacto de novas aquisições se faz presente também na neurocirurgia.
Roberto S. Martins, Mario G. Siqueira
doaj   +1 more source

Mitochondrial Stress Links Environmental Triggers with Pro-Inflammatory Signaling in Crohn’s Disease

open access: yesAntioxidants, 2023
Inflammatory Bowel Diseases (IBD) are a group of chronic, inflammatory disorders of the gut. The incidence and activity of IBD are determined by both genetic and environmental factors.
Flores Martín-Reyes   +15 more
doaj   +1 more source

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

open access: yesAllergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane   +12 more
wiley   +1 more source

Hipertermia magnética como terapia oncológica de precisão: uma revisão crítica

open access: yesRevista Binacional Brasil - Argentina
O câncer é um desafio à saúde pública, exigindo respostas terapêuticas eficazes. Embora as abordagens tradicionais — cirurgia, radioterapia e quimioterapia — permaneçam como pilares da oncologia, frequentemente são acompanhadas por elevada toxicidade e ...
Matheus Fernandes Muniz de Almeida   +2 more
doaj   +1 more source

Physiological and Sleep Profiles in Insomnia, OSA and COMISA: A Comparative Study in Portugal and Spain

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Insomnia and obstructive sleep apnea (OSA) are common sleep disorders that often co‐occur as comorbid insomnia and sleep apnea (COMISA), worsening health outcomes. This study characterized and compared the physiological and sleep profiles of insomnia, OSA and COMISA in population‐based datasets from Portugal (n = 147) and Spain (n = 264 ...
Margarida Carvalho   +9 more
wiley   +1 more source

Nanosilver: Propriedades, Aplicações e Impactos na Saúde Pública e Meio Ambiente

open access: yesVigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2013
A nanotecnologia se desenvolveu rapidamente durante a última década, com aplicações em áreas estratégicas, incluindo saúde, energia, eletrônica, entre outras.
Patricia F. M. Nogueira   +2 more
doaj   +1 more source

Association of Post‐Oral Glucose Tolerance Test Hypoglycaemia With Clinical Features, Incident Diabetes and Mortality in the Di@bet.es Cohort

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7430-7442, August 2026.
ABSTRACT Aims To investigate the association of post‐oral glucose tolerance test (OGTT) hypoglycaemia with clinical features, incident diabetes and mortality. Materials and Methods This population‐based cohort study included 2924 adults (median age 49 years, 1680 women) without known diabetes who underwent a 75‐g OGTT as part of the Di@bet.es Study ...
Tomás González‐Vidal   +14 more
wiley   +1 more source

Real‐world effectiveness of chemotherapy regimens after immunotherapy in patients with advanced melanoma in Spain: Results from the GEM1801 study

open access: yesCancer, Volume 132, Issue 14, 15 July 2026.
ABSTRACT Background Chemotherapy schemes have historically shown low efficacy in patients with metastatic melanoma and have been replaced by immunotherapy and targeted therapy. This work aimed to study whether chemotherapy remains an option after progression to immunotherapy in specific contexts.
Miguel‐Ángel Berciano‐Guerrero   +29 more
wiley   +1 more source

Sistemas Multivalentes para Nanomedicina

open access: yes, 2020
La nanomedicina es la aplicación de la nanotecnología y herramientas asociadas a la medicina, mejorando el diagnóstico la prevención y el tratamiento de las enfermedades. Desde el punto de vista de la química, una de las herramientas más utilizadas son los sistemas multivalentes, que son moléculas que contienen múltiples grupos funcionales dispuestos ...
Royo, Miriam   +8 more
openaire   +1 more source

Home - About - Disclaimer - Privacy