Results 91 to 100 of about 74,551 (265)
Advanced Science, EarlyView.We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin +10 more
wiley +1 more source
Viruses as nanomedicine for cancer
, 2016 Narayanasamy Badrinath,1 Jeong Heo,2 So Young Yoo1,3 1BIO-IT Foundry Technology Institute, 2Department of Internal Medicine, College of Medicine, Medical Research Institute, Pusan National University, Busan, 3Research Institute for Convergence of ...
Yoo SY, Badrinath N, Heo J
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Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Advanced Science, EarlyView.Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source
Nanomedicine concepts in the general medical curriculum: initiating a discussion
, 2015 Aldrin E Sweeney Center for Teaching & Learning, Ross University School of Medicine, Roseau, Commonwealth of Dominica Abstract: Various applications of nanoscale science to the field of medicine have resulted in the ongoing development of the ...
Sweeney AE
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Advanced Science, EarlyView.This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source
Nanomedicine applications in women's health: state of the art
, 2018 Oliver Lloyd-Parry, Charlotte Downing, Eisa Aleisaei, Celine Jones, Kevin Coward Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK Abstract: State-of-the-art applications of ...
Downing C +4 more
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Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
An annotated corpus with nanomedicine and pharmacokinetic parameters
, 2017 Nastassja A Lewinski,1 Ivan Jimenez,1 Bridget T McInnes2 1Department of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, VA, 2Department of Computer Science, Virginia Commonwealth University, Richmond, VA, USA Abstract:
Jimenez I, McInnes BT, Lewinski NA
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Biodistribution of Nanomedicines [PDF]
Molecular Pharmaceutics, 2008 Eric, Simanek, Anil K, Patri
openaire +2 more sources
Advanced Science, EarlyView.A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu +17 more
wiley +1 more source