Results 71 to 80 of about 169,839 (342)

Multiplex Modular Nanorobotic Systems with Catalytic Activity under Magnetic Navigation

Advanced Functional Materials, EarlyView.
We present modular nanorobots composed of a magnetic propulsion module and different extension modules carrying functional activities, assembled via DNA base pairing. The system integrates propulsion, optical tracking, enzymatic catalysis, and cell docking in a programmable manner.
Voichita Mihali, Xinan Huang, Lucie Motyckova, Nicolas Moreno Gomez, Michal Skowicki, Cora‐Ann Schoenenberger, Peer Fischer, Cornelia G. Palivan   +7 more
wiley   +1 more source

Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]

, 2015
Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey, Jakobsson, Eric, Sun, Jie, Wang, Yingxiao   +3 more
core   +2 more sources

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Environmental Barriers To Transfer And Commercialize Nanomedicine Research Results In Iran: A Qualitative Research

پیاورد سلامت, 2014
Background and Aim: Nanomedicine is growing very fast. Transfer and commercialization of research results in Nanomedicine is a missing link between technology and market. This is affected by some factors which are barriers to commercialization.
Seyed Reza Hejazi, Payam Mansoor Hosseini   +1 more
doaj   +2 more sources

Microneedle-mediated nanomedicine to enhance therapeutic and diagnostic efficacy

Nano Convergence
Nanomedicine has been extensively explored for therapeutic and diagnostic applications in recent years, owing to its numerous advantages such as controlled release, targeted delivery, and efficient protection of encapsulated agents.
Yuyang Zuo, Rujie Sun, Nuala Del Piccolo, Molly M. Stevens   +3 more
doaj   +1 more source

Reflections on Emerging Technologies in Nanomedicine

Erciyes Medical Journal, 2020
Nanomedicine technologies seem to play an increasing role in modern medicine. Although there are many challenges, it is important to consider emerging technologies that may impact nanomedicine. To establish a rational basis for such consideration in this
Munis Dündar, Adam Mechler, Jean-pierre Alcaraz, Gary Henehan, Satya Prakash, Ratnesh Lal, Donald Martin   +6 more
doaj   +1 more source

Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout

BMC Pharmacology and Toxicology, 2022
Background Allopurinol (ALP), a xanthine oxidase inhibitor, is a first line drug for the treatment of gout and hyperuricemia. Being the member of BCS class II drugs, ALP has solubility problem, which affects its bioavailability.
Zakir Ali, Fakhar ud Din, Fatima Zahid, Saba Sohail, Basalat Imran, Salman Khan, Maimoona Malik, Alam Zeb, Gul Majid Khan   +8 more
doaj   +1 more source

Formation of octapod MnO nanoparticles with enhanced magnetic properties through kinetically-controlled thermal decomposition of polynuclear manganese complexes [PDF]

, 2014
Polynuclear manganese complexes are used as precursors for the synthesis of manganese oxide nanoparticles (MnO NPs). Altering the thermal decomposition conditions can shift the nanoparticle product from spherical, thermodynamically-driven NPs to unusual,
Abdulwahab, Catherine C. Berry, Chen, Chen, Donald A. MacLaren, Douglas, Floriana Tuna, Folch, Fraser J. Douglas, Hou, Hu, Huang, Huang, Lis, Liu, Liu, Maccarini, Mark Murrie, Mishra, Na, Ould-Ely, Park, Patzke, Salazar-Alvarez, Santhanagopalan, Seo, Tong, Vincent, William M. Holmes, Xing, Zhang, Zhong, Zitoun   +32 more
core   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source