Results 141 to 150 of about 105,790 (331)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation

open access: yesAdvanced Materials, EarlyView.
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju   +7 more
wiley   +1 more source

Holographic Whole‐Object Photopolymerization Preserving Director Alignment in Liquid Crystalline Actuators

open access: yesAdvanced Materials, EarlyView.
Holographic microlithography enables the fabrication of fully connected 3D liquid crystalline structures in a single exposure. The process maintains precise control over the director orientation within the entire object, preventing local director distortions typically observed in sequential printing.
Lovish Gulati   +8 more
wiley   +1 more source

Hybrid metallic nanozyme with nitric oxide-releasing photothermal coating for accelerated infected diabetic wound healing

open access: yesJournal of Nanobiotechnology
Infected diabetic wounds are prone to developing bacterial biofilms and are difficult to treat due to a lack of strategies that can eliminate drug-resistant bacteria.
Sri Ganga Padaga   +5 more
doaj   +1 more source

Revolutionizing head and neck squamous cell carcinoma treatment with nanomedicine in the era of immunotherapy

open access: yesFrontiers in Immunology
Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignant tumor globally. Despite advancements in treatment methods, the overall survival rate remains low due to limitations such as poor targeting and low bioavailability, which result in the
Hong-Xia Li   +9 more
doaj   +1 more source

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

open access: yesAdvanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung   +4 more
wiley   +1 more source

Enhancing cancer immunotherapy with nanomedicine

open access: yesNature reviews. Immunology, 2020
D. Irvine, Eric L. Dane
semanticscholar   +1 more source

Laser‐Synthesized Amorphous PdSe2‐x Nanoparticles: A Defect‐Rich Platform for High‐Efficiency SERS, Photocatalysis, and Photothermal Conversion

open access: yesAdvanced Materials Interfaces, EarlyView.
Using femtosecond ablation, we show that an ordered, stoichiometric crystalline PdSe2 target can be controllably converted into a stable, disordered, non‐stoichiometric, and highly functional amorphous nanomaterial, PdSe2−x${\rm PdSe}_{2-x}$. The obtained nanoparticles offer significant advantages over conventional planar plasmon‐free substrates due to
Andrei Ushkov   +18 more
wiley   +1 more source

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