Results 221 to 230 of about 105,790 (331)

Therapeutic efficacy of nanomedicines for prostate cancer: An update

, 2016
Vinoth‐Kumar Lakshmanan
openalex   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Synergetic Photodynamic-Photothermal-Chemotherapy Dual Targeting Nanoplatform Effective Against Breast Cancer in-Mice Model [Retraction]. [PDF]

Int J Nanomedicine
europepmc   +1 more source

Nanochelate-based BCc1 delivery and its impact on key regulatory pathways in BALB/c breast cancer: An analysis of <i>Beclin-1</i>, <i>ATG-4B</i>, <i>ATG-7</i>, and <i>mTOR</i> expression. [PDF]

Biochem Biophys Rep
Moheb Afzali F, Heshmati M, Salimi A, Kalanaky S, Fakharzadeh S, Hafizi M, Akbari ME, Nazaran MH, Hashemi M.   +8 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Superparamagnetic Iron Oxide Nanoparticles Modified with Polyethylenimine and Galactose for siRNA Targeted Delivery in Hepatocellular Carcinoma Therapy [Retraction]. [PDF]

Int J Nanomedicine
europepmc   +1 more source

Nanomedical approaches to deplete intracellular glutathione in oncology. [PDF]

Chem Sci
Bonet-Aleta J, Hueso JL, Mosseri A, Santamaria J.   +3 more
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Targeted Multifunctional Nanoplatform for Imaging-Guided Precision Diagnosis and Photothermal/Photodynamic Therapy of Orthotopic Hepatocellular Carcinoma [Retraction]. [PDF]

Int J Nanomedicine
europepmc   +1 more source

Erratum: Albumin-seeking dyes with adjustable assemblies <i>in situ</i> enable programmable imaging windows and targeting tumor imaging: Erratum. [PDF]

Theranostics
Du Y, Xu J, Han T, Jiang Z, Zhang Y, Li J, Chen X, Zhu S.   +7 more
europepmc   +1 more source