Results 161 to 170 of about 4,614 (205)
Multifunctional nanoparticles with combined diagnostic and therapeutic functions show great promise in nanomedicine. Herein, we develop an organic photodynamic therapy (PDT) system based on polyethylene glycol (PEG)-coated nanomicelles conjugated with ...
Liang Cheng +2 more
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Methotrexate (MTX) is the first line agent for therapy against rheumatoid arthritis (RA); however, orally its efficacy is hampered by poor solubility, less permeability, short plasma half-life, and reduced bioavailability.
Maimoona Qindeel +2 more
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Polymeric nanomicelles of curcumin: Potential applications in cancer
International Journal of Pharmaceutics, 2022Natural compounds, primarily derived from plants, have been isolated and evaluated as alternative and complementary treatments for cancer. Curcumin has been proven to be beneficial in cancer therapy due to its multiple effects on cell signaling pathways, although the application of curcumin is limited due to its low oral bioavailability. Nanotechnology-
Leila, Farhoudi +4 more
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Nanomicelles Array for Ultrahigh‐Density Data Storage
Small, 2022AbstractHigh‐density data storage devices based on organic and polymer materials are currently restricted by two key issues, size limitations and uniformity of memory cells. Herein, one triblock polymer is synthesized by ring‐opening metathesis polymerization, where the polymer contains an electron‐donor‐acceptor (A1D) segment, an electron‐acceptor (A2)
Guan Wang +6 more
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Nutraceuticals provide many biological benefits besides their basic nutritional value. However, their biological efficacies are often limited by poor absorption and low bioavailability.
Yun Zeng, Gang Liu
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Water Encapsulation by Nanomicelles
Angewandte Chemie, 2014AbstractReported is the hydration of nanomicelles in the gas‐phase using spectroscopic methods and quantum chemical calculations. A fine‐tuning of the experimental conditions allowed formation of a propofol trimer and tetramer with a water molecule and to determine the structure of the aggregates.
Iker, León +4 more
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Age-related macular degeneration is a multifactorial disease affecting the posterior segment of the eye and is characterized by aberrant nascent blood vessels that leak blood and fluid. It ends with vision loss. In the present study, artemisinin which is
Chandrasekar Ponnusamy +2 more
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Polymeric nanomicelles for cancer theragnostics
International Journal of Polymeric Materials and Polymeric Biomaterials, 2017ABSTRACTRecently, interdisciplinary research in cancer diagnosis and therapy has evolved to the point where nanotechnology particularly polymeric nano delivery systems are utilized for theragnostic applications. Nanoscale are being trialed for specific targeting-delivery of drugs, micelles, antibody, DNA, protein etc.
Anjusha Mohan +2 more
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Supramolecular Dual Drug Nanomicelles for Circumventing Multidrug Resistance
ACS Biomaterials Science & Engineering, 2021Overexpressed P-glycoprotein (P-gp), as the key factor in multidrug resistance (MDR), can greatly reduce intracellular drug levels as a result of chemotherapeutic drug efflux out of cancer cells. Although various P-gp antagonists have been developed to circumvent the MDR effect, the common strategies of physical entrapment or chemical conjugation of ...
Muqiong Li +4 more
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Preparation and in vitro evaluation of ampelopsin-loaded nanomicelles
China Journal of Chinese Materia Medica, 2016To improve the solubility and antitumor activity of ampelopsin, ampelopsin-loaded nanomicelles from the mixture of pluronic F127 and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS1000) were prepared by film-thin hydration method, in order to optimize the process conditions and physicochemical properties.
Ren-Jie, Huang +2 more
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