Results 161 to 170 of about 4,614 (205)

Dual-Modality Positron Emission Tomography/Optical Image-Guided Photodynamic Cancer Therapy with Chlorin e6-Containing Nanomicelles

open access: yesACS Nano, 2016
Multifunctional nanoparticles with combined diagnostic and therapeutic functions show great promise in nanomedicine. Herein, we develop an organic photodynamic therapy (PDT) system based on polyethylene glycol (PEG)-coated nanomicelles conjugated with ...
Liang Cheng   +2 more
exaly   +2 more sources

Surfactant-Free, Self-Assembled Nanomicelles-Based Transdermal Hydrogel for Safe and Targeted Delivery of Methotrexate against Rheumatoid Arthritis

open access: yesACS Nano, 2020
Methotrexate (MTX) is the first line agent for therapy against rheumatoid arthritis (RA); however, orally its efficacy is hampered by poor solubility, less permeability, short plasma half-life, and reduced bioavailability.
Maimoona Qindeel   +2 more
exaly   +2 more sources
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Polymeric nanomicelles of curcumin: Potential applications in cancer

International Journal of Pharmaceutics, 2022
Natural compounds, primarily derived from plants, have been isolated and evaluated as alternative and complementary treatments for cancer. Curcumin has been proven to be beneficial in cancer therapy due to its multiple effects on cell signaling pathways, although the application of curcumin is limited due to its low oral bioavailability. Nanotechnology-
Leila, Farhoudi   +4 more
openaire   +2 more sources

Nanomicelles Array for Ultrahigh‐Density Data Storage

Small, 2022
AbstractHigh‐density data storage devices based on organic and polymer materials are currently restricted by two key issues, size limitations and uniformity of memory cells. Herein, one triblock polymer is synthesized by ring‐opening metathesis polymerization, where the polymer contains an electron‐donor‐acceptor (A1D) segment, an electron‐acceptor (A2)
Guan Wang   +6 more
openaire   +2 more sources

Application of Nanomicelles in Enhancing Bioavailability and Biological Efficacy of Bioactive Nutrients

open access: yesPolymers, 2022
Nutraceuticals provide many biological benefits besides their basic nutritional value. However, their biological efficacies are often limited by poor absorption and low bioavailability.
Yun Zeng, Gang Liu
exaly   +2 more sources

Water Encapsulation by Nanomicelles

Angewandte Chemie, 2014
AbstractReported is the hydration of nanomicelles in the gas‐phase using spectroscopic methods and quantum chemical calculations. A fine‐tuning of the experimental conditions allowed formation of a propofol trimer and tetramer with a water molecule and to determine the structure of the aggregates.
Iker, León   +4 more
openaire   +2 more sources

Development and Evaluation of Polyvinylpyrrolidone K90 and Poloxamer 407 Self-Assembled Nanomicelles: Enhanced Topical Ocular Delivery of Artemisinin

open access: yesPolymers, 2021
Age-related macular degeneration is a multifactorial disease affecting the posterior segment of the eye and is characterized by aberrant nascent blood vessels that leak blood and fluid. It ends with vision loss. In the present study, artemisinin which is
Chandrasekar Ponnusamy   +2 more
exaly   +2 more sources

Polymeric nanomicelles for cancer theragnostics

International Journal of Polymeric Materials and Polymeric Biomaterials, 2017
ABSTRACTRecently, interdisciplinary research in cancer diagnosis and therapy has evolved to the point where nanotechnology particularly polymeric nano delivery systems are utilized for theragnostic applications. Nanoscale are being trialed for specific targeting-delivery of drugs, micelles, antibody, DNA, protein etc.
Anjusha Mohan   +2 more
openaire   +1 more source

Supramolecular Dual Drug Nanomicelles for Circumventing Multidrug Resistance

ACS Biomaterials Science & Engineering, 2021
Overexpressed P-glycoprotein (P-gp), as the key factor in multidrug resistance (MDR), can greatly reduce intracellular drug levels as a result of chemotherapeutic drug efflux out of cancer cells. Although various P-gp antagonists have been developed to circumvent the MDR effect, the common strategies of physical entrapment or chemical conjugation of ...
Muqiong Li   +4 more
openaire   +2 more sources

Preparation and in vitro evaluation of ampelopsin-loaded nanomicelles

China Journal of Chinese Materia Medica, 2016
To improve the solubility and antitumor activity of ampelopsin, ampelopsin-loaded nanomicelles from the mixture of pluronic F127 and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS1000) were prepared by film-thin hydration method, in order to optimize the process conditions and physicochemical properties.
Ren-Jie, Huang   +2 more
openaire   +2 more sources

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