Results 51 to 60 of about 4,614 (205)

Combined Ibuprofen-Nanoconjugate Micelles with E-Selectin for Effective Sunitinib Anticancer Therapy

International Journal of Nanomedicine, 2022
Xianhu Zeng,1 Yi Teng,1 Chunrong Zhu,2 Zhipeng Li,1 Tian Liu,3 Yong Sun,1 Shangcong Han1 1Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, People’s Republic of China; 2Department of Pharmacy Intravenous Admixture Service ...
Zeng X, Teng Y, Zhu C, Li Z, Liu T, Sun Y, Han S   +6 more
doaj  

A peptide-DNA hybrid bio-nanomicelle and its application for detection of caspase-3 activity

Frontiers in Chemistry, 2022
Bio-nanomicelles based on biomaterials such as nucleic acids, peptides, glycans, and lipids have developed rapidly in the field of bioanalysis. Although DNA and peptides have unique advantages, unfortunately, there are few bio-nanomicelles integrating ...
Fan Zhang, Changqing Mao, Siyu Cao, Runchi Zhang, Yi Guo, Guifang Chen, Chang Feng   +6 more
doaj   +1 more source

Formulation of Nanomicelles Loaded with Cannabidiol as a Platform for Neuroprotective Therapy

Pharmaceutics, 2022
The present study is focused on the development of cannabidiol-loaded polymeric nanomicelles as a drug delivery system with neuroprotective effects. Cannabidiol was loaded in Pluronic micelles (Pluronic P123 or its combination with Pluronic F127) possessing an average diameter smaller than 50 nm and high encapsulation efficiency for the hydrophobic ...
Yordan Yordanov, Denitsa Stefanova, Ivanka Spassova, Daniela Kovacheva, Virginia Tzankova, Spiro Konstantinov, Krassimira Yoncheva   +6 more
openaire   +3 more sources

OpiCa1-PEG-PLGA nanomicelles antagonize acute heart failure induced by the cocktail of epinephrine and caffeine

Materials Today Bio, 2023
Background: Reducing Ca2+ content in the sarcoplasmic reticulum (SR) through ryanodine receptors (RyRs) by calcin is a potential intervention strategy for the SR Ca2+ overload triggered by β-adrenergic stress in acute heart diseases.
Jun Li, Fei Wang, Xinyan Liu, Zhixiao Yang, Xiaoyu Hua, Hongqiao Zhu, Carmen R. Valdivia, Li Xiao, Songyu Gao, Héctor H. Valdivia, Liang Xiao, Jinming Wang   +11 more
doaj   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Recent development of polymer nanomicelles in the treatment of eye diseases

Frontiers in Bioengineering and Biotechnology, 2023
The eye, being one of the most intricate organs in the human body, hosts numerous anatomical barriers and clearance mechanisms. This highlights the importance of devising a secure and efficacious ocular medication delivery system. Over the past several decades, advancements have been made in the development of a nano-delivery platform based on ...
Ruijun Cai, Ling Zhang, Hao Chi
openaire   +3 more sources

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Dual Functioned Hexapeptide‐Coated Lipid‐Core Nanomicelles Suppress Toll‐Like Receptor‐Mediated Inflammatory Responses through Endotoxin Scavenging and Endosomal pH Modulation

Advanced Science, 2023
Excessive activation of Toll‐like receptor (TLR) signaling pathways and the circulating endotoxin are key players in the pathogenesis of many acute and chronic inflammatory diseases.
Yuting Ji, Liya Sun, Yuan Liu, Yanhui Li, Tongxuan Li, Jiameng Gong, Xiali Liu, Huiqiang Ma, Jingying Wang, Bing Chen, Shan‐Yu Fung, Hong Yang   +11 more
doaj   +1 more source

Navigating the future of nano‐pesticides: A perspective on design, efficacy, mechanisms, and environmental stewardship

iMeta, EarlyView.
Nano‐pesticides are driving a paradigm shift toward sustainable plant protection. This review systematically synthesizes recent advances across four interconnected domains: (i) intelligent formulation design for targeted delivery and controlled release; (ii) interfacial behavior regulation to enhance foliar deposition; (iii) multi‐omics elucidation of ...
Xile Deng, Feiying Zhu, Heng Qiao, Wenjie Shangguan, Qin Yu, Sandeep Sharma, Vijayakumar Shanmugam, Yanan Deng, Yudan Wu, Pengyue Zhao, Ullah Farman, Lidong Cao, Shuo Yan, Zhichao Dong, Lianyang Bai   +14 more
wiley   +1 more source

Design, characterization, and intracellular trafficking of biofunctionalized chitosan nanomicelles

Biointerphases, 2020
The hydrophobically modified glycol chitosan (HGC) nanomicelle has received increasing attention as a promising platform for the delivery of chemotherapeutic drugs. To improve the tumor selectivity of HGC, here an avidin and biotin functionalization strategy was applied.
Weiyi Li, Giulia Suarato, Jillian M Cathcart, Paul R Sargunas, Yizhi Meng   +4 more
openaire   +3 more sources