Results 61 to 70 of about 4,614 (205)

Oleic Acid Copolymer as A Novel Upconversion Nanomaterial to Make Doxorubicin-Loaded Nanomicelles with Dual Responsiveness to pH and NIR

Pharmaceutics, 2020
Oleic acid (OA) as main component of plant oil is an important solvent but seldom used in the nanocarrier of anticancer drugs because of strong hydrophobicity and little drug release.
Jin Zhang, Xiaoyue Tang, Chuanqing Huang, Zeyu Liu, Yong Ye   +4 more
doaj   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Near-Infrared Frequency Upconversion Luminescence Bioimaging Based on Cyanine Nanomicelles

, 2022
Upconversion optical imaging has great application prospects in biomedical imaging. However, research on molecular upconversion luminescence materials is very limited. In this study, a cyanine dye modified using polyethylene glycol is reported, which has
Yuhao Li (1559569), Xiang Wang (127867), Jinliang Liu (560024), Yun Sun (451368), Fei Huang (9205), Yuqing Miao (6792086)   +5 more
core   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Self-assembled latanoprost loaded soluplus nanomicelles as an ophthalmic drug delivery system for the management of glaucoma

Scientific Reports
Glaucoma, a leading cause of blindness due to elevated intraocular pressure (IOP), is managed with medications like latanoprost (LAT), a prostaglandin analogue, to enhance aqueous outflow.
Shazma Gohar, Zafar Iqbal, Fazli Nasir, Muzna Ali Khattak, Gul e Maryam, Sadia Pervez, Fawaz Alasmari, Steven H. Neau, Syeda Rabqa Zainab, Arbab Tahir Ali, Altaf ur Rahman   +10 more
doaj   +1 more source

Peptide‐based responsive molecular fluorescent probes for precision oncology

Responsive Materials, EarlyView.
Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang, Wen Liu, Jiahao Zhang, Wanqi Wang, Zhicheng Jin, Yuqi Tang, Quan Li   +6 more
wiley   +1 more source

Thermosensitive Nanostructured Coacervates Developed by Mixing ABA‐ and AB‐Block Copolymers and Their Unique Sustained Release of Nano‐Micelles in a Regulated Manner

Small, EarlyView.
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira, Hiroshi Kamizawa, Yujiro Hamada, Wataru Fushimoto, Hiroshi Y. Yoshikawa, Yuji Higaki, Atsushi Takahara, Takeshi Mori, Yoshiki Katayama, Akihiro Kishimura   +9 more
wiley   +1 more source

Combined Effects of Core Rigidity and Surface Charge of Polymeric Nanomicelles on the Cellular Uptake Efficiency

, 2023
To minimize macrophage recognition and rapid clearance, polymeric nanodrug carriers (e.g., nanomicelles) are typically engineered to be negatively charged and PEGylated.
Yuejian He (17013511), Mingheng Xu (17013520), Peiyi He (17013517), Xiaoxi Zhao (266795), Guifeng Miao (17013508), Xiaorui Wang (237883), Zhanhao Shang (17013514)   +6 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

The effect of berberine nanomicelles on hepatic cirrhosis in bile duct-ligated rats [PDF]

Nanomedicine Journal, 2018
Objective (s): The anti-fibrotic effect of chronic berberine (BBR) had demonstrated previously in a rat model of bile duct ligation (BDL). The aim of present study was to investigate hepatoprotective effect of BBR nanomicelles on liver cirrhosis induced ...
Seyed Pouyan Pishva, eyyedeh Elaheh Mousavi, Zahra Mousavi, Mahmoud Reza Jaafari, Ahmad Reza Dehpour, Seyed Mahdi Rezayat Sorkhabadi   +5 more
doaj   +1 more source