Results 51 to 60 of about 658,725 (274)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Stretchable conductive nanocomposite based on alginate hydrogel and silver nanowires for wearable electronics

open access: yesAPL Materials, 2019
Wearable electronic devices are used to perform various electronic functions on the human skin, and their mechanical softness while maintaining high performances is critical. Therefore, there is a need to develop novel materials with outstanding softness
Chanhyuk Lim   +5 more
doaj   +1 more source

Curved neuromorphic image sensor array using a MoS2-organic heterostructure inspired by the human visual recognition system

open access: yesNature Communications, 2020
Designing efficient bio-inspired visual recognition system remains a challenge. Here the authors present a curved neuromorphic image sensor array based on a heterostructure of MoS2 and pV3D3 integrated with a plano-convex lens for efficient image ...
Changsoon Choi   +13 more
doaj   +1 more source

Stabilization of colloidal suspensions by means of highly-charged nanoparticles

open access: yes, 2004
We employ a novel Monte Carlo simulation scheme to elucidate the stabilization of neutral colloidal microspheres by means of highly-charged nanoparticles [V. Tohver et al., Proc. Natl. Acad. Sci. U.S.A. 98, 8950 (2001)].
Erik Luijten   +4 more
core   +1 more source

High-resolution surface plasmon imaging of gold nanoparticles by energy-filtered transmission electron microscopy [PDF]

open access: yes, 2009
We demonstrate the imaging capabilities of energy-filtered transmission electron microscopy at high-energy resolution in the low-energy-loss region, reporting the direct image of a surface plasmon of an elongated gold nanoparticle at energies around 1 eV.
Andreas Trügler   +7 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Machine Learning Classification Model to Label Sources Derived from Factor Analysis Receptor Models for Source Apportionment

open access: yesAerosol and Air Quality Research, 2023
Factor analysis (FA) receptor models are widely used for source apportionment (SA) due to their ability to extract the source contribution and profile from the data.
Vikas Kumar   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Nanoparticle Reinforced Polymers [PDF]

open access: yesPolymers, 2019
The beginning of nanomaterials and nanoscience dates back to 1959 when the Nobel laureate in Physics Richard Feynman gave the famous lecture entitled “There’s Plenty of Room at the Bottom [...]
openaire   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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