Results 51 to 60 of about 658,725 (274)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Wearable electronic devices are used to perform various electronic functions on the human skin, and their mechanical softness while maintaining high performances is critical. Therefore, there is a need to develop novel materials with outstanding softness
Chanhyuk Lim +5 more
doaj +1 more source
Designing efficient bio-inspired visual recognition system remains a challenge. Here the authors present a curved neuromorphic image sensor array based on a heterostructure of MoS2 and pV3D3 integrated with a plano-convex lens for efficient image ...
Changsoon Choi +13 more
doaj +1 more source
Stabilization of colloidal suspensions by means of highly-charged nanoparticles
We employ a novel Monte Carlo simulation scheme to elucidate the stabilization of neutral colloidal microspheres by means of highly-charged nanoparticles [V. Tohver et al., Proc. Natl. Acad. Sci. U.S.A. 98, 8950 (2001)].
Erik Luijten +4 more
core +1 more source
High-resolution surface plasmon imaging of gold nanoparticles by energy-filtered transmission electron microscopy [PDF]
We demonstrate the imaging capabilities of energy-filtered transmission electron microscopy at high-energy resolution in the low-energy-loss region, reporting the direct image of a surface plasmon of an elongated gold nanoparticle at energies around 1 eV.
Andreas Trügler +7 more
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Factor analysis (FA) receptor models are widely used for source apportionment (SA) due to their ability to extract the source contribution and profile from the data.
Vikas Kumar +3 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Nanoparticle Reinforced Polymers [PDF]
The beginning of nanomaterials and nanoscience dates back to 1959 when the Nobel laureate in Physics Richard Feynman gave the famous lecture entitled “There’s Plenty of Room at the Bottom [...]
openaire +3 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source

