Results 61 to 70 of about 305,780 (267)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation

open access: yesiScience, 2019
Summary: Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with cereblon (CRBN), a substrate receptor subunit of the CRL4 E3 ubiquitin ligase complex.
Hideki Ando   +13 more
doaj   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan   +4 more
wiley   +1 more source

Facile Synthesis Toward Surface Decorated Ir1Ox@Pd35 with Low Iridium Content for Highly Efficient and Durable Proton Exchange Membrane Water Electrolyzer

open access: yesChemElectroChem
Herein, we introduce an iridium‐decorated palladium nanocluster (Ir1Ox@Pd35) synthesized via an epoxide‐assisted sol‐gel method. The nanocluster had a unique surface‐decorated structure, as confirmed by transmission electron microscopy (TEM) and ...
Hosung Choi   +9 more
doaj   +1 more source

Structural and Thermodynamic Understandings in Mn‐Based Sodium Layered Oxides during Anionic Redox

open access: yesAdvanced Science, 2020
A breakthrough utilizing an anionic redox reaction (O2−/On−) for charge compensation has led to the development of high‐energy cathode materials in sodium‐ion batteries.
Seok Mun Kang   +11 more
doaj   +1 more source

Impact of MgO Additions on the Oxidation Resistance and Compression Behavior of Vanadium Alloys

open access: yesAdvanced Engineering Materials, EarlyView.
An increase in oxidation resistance at 600 °C is achieved for alloys containing more than 2.5 wt.% MgO. It has been established that, along with V2O5, MgO6V2, and Mg2O7V2 are formed, which are presumed to enhance oxidative stability. Furthermore, the possible transformation of Mg‐vanadates through reaction with CO2, which presumably occurs in this ...
Ievgen Solodkyi   +5 more
wiley   +1 more source

Nanoparticle to Nanoparticle Bioorthogonal Detection of Atherosclerosis

open access: yesACS Applied Materials & Interfaces
In vivo identification and characterization of atherosclerosis is a promising approach for the development of novel therapies and personalized treatments. Among the methods for this in vivo identification, the use of pretargeted imaging shows very large probe uptakes and excellent selectivity.
Muñoz-Hernando, María   +7 more
openaire   +5 more sources

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source

Self‐Cleaning Sensor Surfaces for Long‐Term Environmental Monitoring

open access: yesAdvanced Engineering Materials, EarlyView.
Long‐term use of unattended outdoor sensors without soiling or biofouling is achieved through generation of a micro‐ and nanorough cuvette surface by combing hydrophobic nanoparticles with fluorinated polymers, crosslinked and surface‐attached through CHic chemistry. The coating demonstrates self‐cleaning behavior and prolonged outdoor stability, which
Sanam Kumari Rajak   +4 more
wiley   +1 more source

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

open access: yesAdvanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic   +2 more
wiley   +1 more source

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