Results 101 to 110 of about 2,804,865 (380)

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

Advanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez, Hao Zhang, Dhananjay Sah, Juan P. Cata   +3 more
wiley   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Order-disorder phase change in embedded Si nano-particles

, 2011
We investigated the relative stability of the amorphous vs crystalline nanoparticles of size ranging between 0.8 and 1.8 nm. We found that, at variance from bulk systems, at low T small nanoparticles are amorphous and they undergo to an amorphous-to ...
I. Coluzza, Luciano Colombo, Sergio Orlandini, Simone Meloni   +3 more
core   +1 more source

Therapeutic Nanoparticles and Their Targeted Delivery Applications

Molecules, 2020
Nanotechnology offers many advantages in various fields of science. In this regard, nanoparticles are the essential building blocks of nanotechnology. Recent advances in nanotechnology have proven that nanoparticles acquire a great potential in medical ...
Abuzer Alp Yetisgin, Sibel Çetinel, M. Zuvin, A. Koşar, Ozlem Kutlu   +4 more
semanticscholar   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Superparamagnetic nanoparticle ensembles

, 2012
Magnetic single-domain nanoparticles constitute an important model system in magnetism. In particular ensembles of superparamagnetic nanoparticles can exhibit a rich variety of different behaviors depending on the inter-particle interactions.
Allwood, Batlle, Bedanta, Benitez, Berkovsky, Binney, Blundell, Brown, Chen, Chen, Daughton, Denardin, Dormann, El-Hilo, Ge, Hauschild, Iglesias, Jeong, Jiles, Jönsson, Kakazei, Kleemann, Kodama, Luis, Lyubchanskii, Moerup, Moerup, Mydosh, Nogués, Néel, Néel, O. Petracic, Odenbach, O’Handley, Pankhurst, Petracic, Petracic, Petracic, Petracic, Pfeiffer, Provenzano, Rosensweig, Sahoo, Sahoo, Sahoo, Sankar, Scheinfein, Sharrock, Siegmann, Skomski, Skomski, Sun, Terris, Wolf   +53 more
core   +1 more source

Robocasting of a Water‐Based Biopolymer/WO3 Nanopowder Paste as a Precursor to Tungsten Carbide Lattices

Advanced Engineering Materials, EarlyView.
This study demonstrates a novel, additive manufacturing approach to produce complex, porous tungsten carbide structures using water‐based direct ink writing/robocasting. Leveraging a modified commercial printer and heat treatment, the process yields lightweight, electrically conductive 3D architectures capable of supporting a mechanical load.
James Bentley Bevis, Manasi Shah, Sanketh Gombi, Rodrigo Martinez‐Duarte   +3 more
wiley   +1 more source

Synthesis and self-assembly of lipid (DMPC)-conjugated gold nanoparticles

, 2007
Bio-conjugated nanomaterials play a promising role in the development of novel supramolecular structures, molecular machines, and biosensing devices. In this study, lipid-conjugated gold nanoparticles were synthesized and allowed to form a self-assembled
Chatterjee, Subhasish, Gafney, Harry D., Gersten, Bonnie, Krikorian, Markrete   +3 more
core   +1 more source

Multiscale Modeling of Process‐Induced Defects in Fused Filament Fabrication‐Printed Materials

Advanced Engineering Materials, EarlyView.
This study presents a predictive multiscale modeling tool for defect analysis of fused filament fabricated‐printed materials and their performance prediction using a mechanistic data science‐based reduced‐order modeling approach. Process‐induced defects are inherent to additively manufactured parts and significantly influence the performance of printed
Satyajit Mojumder, Derick Suarez, Trevor Abbott, Wing Kam Liu   +3 more
wiley   +1 more source

Drug delivery and nanoparticles: Applications and hazards

International Journal of Nanomedicine, 2008
The use of nanotechnology in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy.
W. D. De Jong, P. Borm
semanticscholar   +1 more source