Results 121 to 130 of about 73,616 (310)

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan   +9 more
wiley   +1 more source

Illumina and Nanopore sequencing in culture-negative samples from suspected lower respiratory tract infection patients

open access: yesFrontiers in Cellular and Infection Microbiology
ObjectiveTo evaluate the diagnostic value of metagenomic sequencing technology based on Illumina and Nanopore sequencing platforms for patients with suspected lower respiratory tract infection whose pathogen could not be identified by conventional ...
Lichao Ma   +10 more
doaj   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

open access: yesAdvanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun   +13 more
wiley   +1 more source

Microenvironment Engineering of Nanopore for Enzyme Accommodation

open access: yes, 2013
Microenvironment Engineering of Nanopore for Enzyme ...
刘佳, 杨启华, 李灿
core  

Black Silicon for Solar Fuels

open access: yesAdvanced Science, EarlyView.
Black silicon couples broadband light harvesting with high‐surface‐area catalytic interfaces, offering a versatile photoelectrode platform for solar‐fuel production. Reaction‐specific analysis highlights trade‐offs involving recombination, chemical instability, catalyst‐induced optical shielding, competing reactions, and mass transport.
Neul Ha, Kaiying Wang, Wooseok Yang
wiley   +1 more source

Detection of Biomolecules on a Nanopore-Microfluidic Platform [PDF]

open access: yes, 2019
In this work, we combined the micropore fabrication process into the fabrication processes of the microfluidic device. With certain post-treatment processes, we integrated solid-state nanopore with the microfluidic chip and created a nanopore ...
Li, Yucheng
core  

Nanopores for Sensing [PDF]

open access: yesACS Sensors, 2018
Yitao Long, J. Justin Gooding
openaire   +2 more sources

Synergistic Effects of Separator Architecture and Electrolyte Chemistry on the Electrochemical Stability of Lithium Ion Batteries With Li–Mn Rich Cathodes and µ‐Si Anodes

open access: yesAdvanced Science, EarlyView.
This work reveals that synergistic engineering of separator architecture and electrolyte chemistry determines the long‐term stability of LMR||µ‐Si cell chemistry. The introduction of N, N‐dimethylsulfamoyl fluoride (DMFSA) as a co‐solvent with fluoroethylene carbonate (FEC) promotes robust interphases on both electrodes, effectively mitigates side ...
Marian Cristian Stan   +12 more
wiley   +1 more source

Rational Molecular Design to Improve Digital Polymer Readout in Aerolysin‐Based Nanopore Sequencing

open access: yesAngewandte Chemie, EarlyView.
Nanopore sensing holds significant yet underexplored potential for decoding synthetic digital polymers. In this study, we synthesized an extensive library of sequence‐defined poly(phosphodiester)s and evaluated their performance in aerolysin‐based sequencing. By systematically optimizing molecular parameters, we identified an ideal combination of coded
Zhaozheng Yang   +9 more
wiley   +2 more sources

Raw Nanopore sequencing read statistics.

open access: yes, 2019
Raw Nanopore sequencing read statistics.
Taylor Sheahan (7037267)   +5 more
core   +1 more source

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