Results 151 to 160 of about 101,026 (352)

Utilization of nanopore direct RNA sequencing to analyze viral RNA modifications

mSystems
Modifications on viral RNAs (vRNAs), either genomic RNAs or RNA transcripts, have complex effects on the viral life cycle and cellular responses to viral infection.
Lu Tan, Zhihao Guo, Xiaoming Wang, Dal Young Kim, Runsheng Li   +4 more
doaj   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Mobile antibiotic resistome in wastewater treatment plants revealed by Nanopore metagenomic sequencing

Microbiome, 2019
Wastewater treatment plants (WWTPs) are recognized as hotspots for horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs). Despite our understanding of the composition and distribution of ARGs in WWTPs, the genetic location, host, and fate ...
You Che, Yu Xia, Lei Liu, An-dong Li, Yu Yang, Tong Zhang   +5 more
semanticscholar   +1 more source

DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout

Advanced Science, EarlyView.
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li, Yesheng Wang, Chunmiao Yu, Siyu Hou, Elli Mylona, Plamena Naydenova, Jingyuan Zhao, Hong Yuan, Jingsong Duan, Hendrik F. P. Runge, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser   +12 more
wiley   +1 more source

Nanopore Sensing [PDF]

Analytical Chemistry, 2016
Wenqing, Shi, Alicia K, Friedman, Lane A, Baker   +2 more
openaire   +2 more sources

N‐Doping Activated Presodiation Enhances Sodium‐Ion Provision in Hard Carbon Anodes

Advanced Science, EarlyView.
Introducing pyrrolic‐N sites enables efficient presodiation and stronger PF6− capture, thus pre ‐ forming a robust inorganic‐rich SEI layer in hard carbon anodes. ABSTRACT Hard carbon (HC) is considered the most promising anode material for commercial sodium‐ion batteries (SIBs), yet it still faces critical challenges such as low initial Coulombic ...
Hua Lin, Wenxing Miao, Yanrong Shi, Guangyi Mao, Ding Ding, Jian Weng, Zhongxiong Fan, Qingchi Xu, Jun Xu   +8 more
wiley   +1 more source

Nanopore Environmental Analysis

JACS Au
As global pollution continues to escalate, timely and accurate monitoring is essential for guiding pollution governance and safeguarding public health. The increasing diversity of pollutants across environmental matrices poses a significant challenge for instrumental analysis methods, which often require labor-intensive and time-consuming sample ...
Xiaofeng Lu, Xiaoyu Du, Dong Zhong, Renjie Li, Junjie Cao, Shuo Huang, Yuqin Wang   +6 more
openaire   +3 more sources

Nanopore-Based Target Sequence Detection.

, 2016
The promise of portable diagnostic devices relies on three basic requirements: comparable sensitivity to established platforms, inexpensive manufacturing and cost of operations, and the ability to survive rugged field conditions.
Trevor J Morin, Tyler Shropshire (2697775), Kyle Briggs (541152), Cindy Huynh (2697772), Hongyun Wang, Xu Liu (276996), Cindy Huynh, Hongyun Wang (225359), William B Dunbar, Tyler Shropshire, Vincent Tabard-Cossa, Vincent Tabard-Cossa (541153), Kyle Briggs, William B. Dunbar (1954906), Trevor J. Morin (309474), Xu Liu   +15 more
core   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Illumina and Nanopore sequencing in culture-negative samples from suspected lower respiratory tract infection patients

Frontiers in Cellular and Infection Microbiology
ObjectiveTo evaluate the diagnostic value of metagenomic sequencing technology based on Illumina and Nanopore sequencing platforms for patients with suspected lower respiratory tract infection whose pathogen could not be identified by conventional ...
Lichao Ma, Chi Zhu, Chi Zhu, Tianli Yan, Yun Hu, Juan Zhou, Yajing Li, Furong Du, Jianping Zhou, Jianping Zhou, Jianping Zhou   +10 more
doaj   +1 more source