Results 211 to 220 of about 73,616 (310)

Long‐Read Pan‐Cancer Transcriptomics Unravel Distinct Alteration Trends Between Gene and Isoform Expression in Tumorigenesis

open access: yesiMetaMed, EarlyView.
Long‐read profiling of 144 tumor‐normal pairs identifies isoform‐level cancer dysregulation independent of gene changes. Our scoring system prioritizes isoform‐driven prognostic genes across cancers. ABSTRACT Tumorigenesis involves transcriptomic alterations at both gene and isoform levels.
Yuying Ding   +9 more
wiley   +1 more source

Sorghum T2T pangenome highlights comprehensive genomic variation

open access: yesiMetaOmics, EarlyView.
Three newly assembled telomere‐to‐telomere (T2T) genomes representing wild, landrace, and transformable germplasm were integrated with seven publicly available T2T genomes to construct a graph‐based pangenome. Comparative analyses revealed extensive centromere divergence, including distinct CEN137 monomer and CEN274 dimer organization, and showed that ...
Lihua Wang   +10 more
wiley   +1 more source

Frontiers in transition‐metal single‐atom electrocatalysts: Design tactics, mechanistic regulation, and electrochemical sensing technologies

open access: yesInfoMat, EarlyView.
This review offers an overview of recent advances in the fundamental properties, synthesis methods, and structural optimization of transition‐metal single‐atom electrocatalysts for electrochemical sensing. It also provides a comprehensive summary of the emerging applications in electrochemical assays based on these materials, along with key challenges ...
Yue Cao   +8 more
wiley   +1 more source

Integrating multiplex digital PCR and long-read sequencing toward standardized genome integrity and purity characterization of rAAV9. [PDF]

open access: yesMol Ther Adv
Kontogiannis T   +7 more
europepmc   +1 more source

Bonding‐chemistry‐guided design of carbon frameworks for rechargeable‐ion batteries

open access: yesInfoMat, EarlyView.
This perspective re‐examines carbon anodes in rechargeable‐ion batteries through the lens of bonding chemistry. By moving beyond conventional morphology‐ and dopant‐based descriptions, it establishes bonding chemistry as a unifying framework for understanding how local atomic interactions govern the structure, surface chemistry, and electrochemical ...
Fei Wang   +9 more
wiley   +1 more source

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