Results 131 to 140 of about 65,196 (347)

Identification of a cryptic unbalanced translocation Der(22)t(12;22)(q24.33;q13.33) in a large Chinese family with Phelan-McDermid syndrome by nanopore sequencing

Scientific Reports
To explore the genetic cause of a four-generation severe intellectual disability in a Chinese family using nanopore sequencing and to provide genetic counseling and reproductive guidance for family members.
Xingwu Wu, Qiang Xu, Ge Chen, Jialyv Huang, Yanying Zhong, Lifeng Tian, Qiongfang Wu, Jia Chen   +7 more
doaj   +1 more source

Structural Variation and 3D Genome‐Driven DNA/RNA Methylation Divergence Contributing to Cotton Fiber Domestication

Advanced Science, EarlyView.
These findings elucidated the crucial role of the “SVs‐3D genome remodeling‐epigenetic modifications‐gene expression” cascade regulatory network in cotton fiber domestication, offering both a theoretical foundation and genetic resources for molecular design breeding in fiber crops.
Lei Shao, Shangkun Jin, Haojie Jiang, Tianyu Pan, Zesheng Rui, Xiaowen Shi, Ting Zhao, Zhanfeng Si, Xueying Guan, Yan Hu, Tianzhen Zhang, Lei Fang   +11 more
wiley   +1 more source

Evaluation of Nanopore Sequencing for Diagnosing Pulmonary Tuberculosis Using Negative Smear Clinical Specimens

Infection and Drug Resistance
Guocan Yu,1 Yanqin Shen,2 Liwei Yao,2 Xudong Xu1 1Zhejiang Tuberculosis Diagnosis and Treatment Center, Hangzhou Red Cross Hospital, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of ...
Yu G, Shen Y, Yao L, Xu X
doaj  

Through-membrane electron-beam lithography for ultrathin membrane applications

, 2017
We present a technique to fabricate ultrathin (down to 20 nm) uniform electron transparent windows at dedicated locations in a SiN membrane for in situ transmission electron microscopy experiments.
Dekker, C., Erdamar, A. K., Heerema, S. J., Kolahdouz, Z., Neklyudova, M., Pandraud, G., Rehfeldt, T., Vicarelli, L., Zandbergen, H. W.   +8 more
core   +2 more sources

Tropheryma whipplei Detection by Nanopore Sequencing in Patients With Interstitial Lung Disease [PDF]

, 2021
Yifan Guo, Lijuan Li, Zhenzhong Li, Lingxiao Sun, Hui Wang   +4 more
openalex   +1 more source

Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics

Advanced Science, EarlyView.
Integrated computational‐biological programming enables secure in vivo data storage by generating code tables from either genomes or gene regulatory networks, expanding the encryption key space by over 100 orders of magnitude. Storing code tables within synthetic genes, genomes, or gene regulatory networks adds an additional layer of security by ...
Jiaxin Xu, Yu Wang, Haibo Zhou, Mingen Li, Yang Wang, Lingwei Wang, Hui Mei, Junbiao Dai, Shanze Chen, Xiaoluo Huang   +9 more
wiley   +1 more source

Chaperone driven polymer translocation through Nanopore: spatial distribution and binding energy

, 2016
Chaperones are binding proteins which work as a driving force to bias the biopolymer translocation by binding to it near the pore and preventing its backsliding. Chaperones may have different spatial distribution. Recently we show the importance of their
Abdolvahab, Rouhollah Haji
core   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

Recent progress in atomistic simulation of electrical current DNA sequencing

, 2014
We review recent advances in the DNA sequencing based on the measurement of transverse electrical currents. Device configurations proposed in the literature are classified according to whether the molecular fingerprints appear as the major (Mode I) or ...
Kim, Han Seul, Kim, Yong-Hoon
core   +1 more source

Wireless Bioelectronic Modulation of Membrane Potential in Glioblastoma Using Carbon Nanotube Porins

Advanced Science, EarlyView.
A schematic illustrating glioblastoma cell membrane modulation using carbon nanotube porins (CNTPs) and an applied voltage. CNTPs enable ion flux leading to changes in membrane potential. This figure summarizes the concept of bioelectronic control of cell membrane voltage.
Fleur Groualle, David Onion, Julie A. Watts, Graham A. Rance, Aleksandr Noy, Beth Coyle, Frankie J. Rawson   +6 more
wiley   +1 more source