Results 161 to 170 of about 37,057 (264)

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

International Journal of Cancer, EarlyView.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah, Emmanuel Addai Gyabaah, Moro Amidu, Zhao Cheng, Fazlur Rahman Talukdar   +4 more
wiley   +1 more source

Rapid on-site universal vertebrate species identification via multi-barcode nanopore sequencing. [PDF]

PLoS One
Patterson EC, Morrison-Lanjouw S, Jobling MA, Wetton JH.   +3 more
europepmc   +1 more source

Application of Artificial Intelligence in Clinical Microbiology: From Research to Practice

iLABMED, EarlyView.
This paper reviews the application of AI in clinical microbiology practice at home and abroad, including rapid pathogen identification, accurate characterization of microbial resistance patterns, optimization of laboratory workflows, and public health interventions.
Ting Ding, Yi‐Wei Tang, Xiaoke Hao
wiley   +1 more source

Rapid Nanopore Sequencing to Identify Bacteria Causing Prosthetic Joint Infections. [PDF]

Antibiotics (Basel)
Wilkinson H, Wright K, McCarthy HS, Perry J, Hulme C, Steele N, Burston B, Townsend R, Cool P.   +8 more
europepmc   +1 more source

Modular automated high‐throughput isolation and phylogenetic identification of bacteria from complex microbiomes

iMetaOmics, EarlyView.
Metagenomic analysis can generate hypotheses about microbiome interactions and function, yet mechanistic understanding is only possible through precise experimentation manipulating its microbiota composition. The high‐throughput isolation of microbiome members thus represents a core resource in this field of research.
Rubén Chaboy‐Cansado, Silvia Talavera‐Marcos, Ramón Gallego‐Simón, Paula Cobeta, Gabriel Roscales, Alberto Rastrojo, Daniel Aguirre de Cárcer   +6 more
wiley   +1 more source

Nanopore Sequencing Reveals Novel Alternative Splice Variants of EZH2 in Pediatric Medulloblastoma. [PDF]

Biomedicines
Ramírez-Chiquito JC, Rosete-Ambriz SA, Olguín-García AC, Eguía-Aguilar MDP, Niembro-Zuñiga AM, Marhx-Bracho A, Perezpeña-Diazconti M, Juárez-Méndez S.   +7 more
europepmc   +1 more source

HiFi based metagenomic assembly strategy provides accuracy near isolated genome resolution in MAG assembly

iMetaOmics, EarlyView.
Recovering high‐contiguity, circular bacterial genomes from complex microbiomes (e.g., gut) is challenged by limitations of short‐read and error‐prone long‐read sequencing. This study comprehensively compares PacBio High‐Fidelity (HiFi) sequencing‐based metagenome‐assembled genomes (MAGs) against Illumina MAGs, Oxford Nanopore Technologies (ONT) MAGs ...
Feilong Deng, Yanhua Han, Minghui Li, Yunjuan Peng, Jianmin Chai, Guan Yang, Ying Li, Jiangchao Zhao   +7 more
wiley   +1 more source

Oxford nanopore sequencing as a useful tool for investigating the population dynamics of invasive begomoviruses in Sicily. [PDF]

Microb Genom
Bertacca S, Rotunno S, Frascati F, Noris E, Accotto GP, Davino S, Miozzi L, Vaira AM.   +7 more
europepmc   +1 more source

Rapid reconstruction of multidrug‐resistant bacterial genomes using CycloneSEQ nanopore sequencing

iMetaOmics, EarlyView.
Multidrug‐resistant (MDR) bacteria commonly harbor highly complex genomes enriched with mobile elements and resistance islands, which are challenging to resolve using short‐read sequencing. Here, we evaluated CycloneSEQ, a newly developed Chinese nanopore sequencing platform, for MDR genome reconstruction.
Kai Peng, Zeyu Tong, Changan Li, Zhichao Li, Xin Lu, Cemil Kurekci, Mashkoor Mohsin, Zhiqiang Wang, Yong‐Xin Liu, Ruichao Li   +9 more
wiley   +1 more source

PACLseq: A Standalone Diagnostic Method for Ph-Like Acute Lymphoblastic Leukemia Using Nanopore Sequencing. [PDF]

MedComm (2020)
Zhang H, Yu H, Chen Y, Jiang K, Huo B, Li J, Liu T, Xie D.   +7 more
europepmc   +1 more source