Results 11 to 20 of about 3,763 (164)

High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis[S] [PDF]

open access: yesJournal of Lipid Research, 2014
Nanoscale secondary ion MS (NanoSIMS) imaging makes it possible to visualize stable isotope-labeled lipids in cells and tissues at 50 nm lateral resolution. Here we report the use of NanoSIMS imaging to visualize lipids in mouse cells and tissues.
Haibo Jiang   +8 more
doaj   +2 more sources

New highlights of phytolith structure and occluded carbon location: 3-D X-ray microscopy and NanoSIMS results [PDF]

open access: yesBiogeosciences, 2015
Phytoliths contain occluded organic compounds called phytC. Recently, phytC content, nature, origin, paleoenvironmental meaning and impact in the global C cycle have been the subject of increasing debate.
A. Alexandre   +6 more
doaj   +3 more sources

Quantitative NanoSIMS provides subcellular concentration and distribution of oligonucleotide therapeutics [PDF]

open access: yes, 2023
Antisense oligonucleotides (ASOs) represent a powerful therapeutic modality that can selectively modulate gene expression. However, ASOs face two major hurdles that restrict their use in the clinic.
Becquart, Cécile
core   +1 more source

Calculation and Interpretation of Substrate Assimilation Rates in Microbial Cells Based on Isotopic Composition Data Obtained by nanoSIMS

open access: yesFrontiers in Microbiology, 2021
Stable isotope probing (SIP) combined with nano-scale secondary ion mass spectrometry (nanoSIMS) is a powerful approach to quantify assimilation rates of elements such as C and N into individual microbial cells.
Lubos Polerecky   +7 more
doaj   +1 more source

Coalescence and directed anisotropic growth of starch granule initials in subdomains of Arabidopsis thaliana chloroplasts

open access: yesNature Communications, 2021
Starch is the major form of energy storage in plant cells and forms discrete, semi-crystalline granules within plastids. Here the authors use electron tomography and nanoSIMS to show that Arabidopsis starch granules initiate in stromal pockets between ...
Léo Bürgy   +7 more
doaj   +1 more source

NanoSIMS and EPMA dating of lunar zirconolite

open access: yesProgress in Earth and Planetary Science, 2021
Zirconolite is a common Zr-rich accessary mineral in mafic rocks. It is also an ideal U–Pb/Pb–Pb chronometer because it commonly contains high U content (mostly 0.1–10 wt%) and negligible initial Pb.
Nian Wang   +4 more
doaj   +1 more source

Heat-Affected-Zone Liquation Cracking in Welded Cast Haynes® 282®

open access: yesMetals, 2019
Varestraint weldability testing and Gleeble thermomechanical simulation of the newly developed cast form of Haynes® 282® were performed to understand how heat-affected-zone (HAZ) liquation cracking is influenced by different preweld heat ...
Sukhdeep Singh, Joel Andersson
doaj   +1 more source

Dissimilatory Fe(III) Reduction Controls on Arsenic Mobilization: A Combined Biogeochemical and NanoSIMS Imaging Approach

open access: yesFrontiers in Microbiology, 2021
Microbial metabolism plays a key role in controlling the fate of toxic groundwater contaminants, such as arsenic. Dissimilatory metal reduction catalyzed by subsurface bacteria can facilitate the mobilization of arsenic via the reductive dissolution of ...
Rebeca Lopez-Adams   +7 more
doaj   +1 more source

Calculation of Single Cell Assimilation Rates From SIP-NanoSIMS-Derived Isotope Ratios: A Comprehensive Approach

open access: yesFrontiers in Microbiology, 2018
The nanoSIMS-based chemical microscopy has been introduced in biology over a decade ago. The spatial distribution of elements and isotopes analyzed by nanoSIMS can be used to reconstruct images of biological samples with a resolution down to tens of ...
Hryhoriy Stryhanyuk   +5 more
doaj   +1 more source

NanoSIMS analysis of arsenic and selenium in cereal grain. [PDF]

open access: yes, 2010
*Cereals are an important source of selenium (Se) to humans and many people have inadequate intakes of this essential trace element. Conversely, arsenic (As) is toxic and may accumulate in rice grain at levels that pose a health risk.
Hawkesford, M J   +38 more
core   +1 more source

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