Results 11 to 20 of about 15,926 (204)

Using design of experiments (DoE) to optimize performance and stability of biomimetic cell membrane-coated nanostructures for cancer therapy

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Cell membrane-covered biomimetic nanosystems have allowed the development of homologous nanostructures to bestow nanoparticles with enhanced biointerfacing capabilities.
Natália Noronha Ferreira, Renata Rank Miranda, Natália Sanchez Moreno, Paula Maria Pincela Lins, Celisnolia Morais Leite, Ana Elisa Tognoli Leite, Thales Rafael Machado, Thaís Regiani Cataldi, Carlos Alberto Labate, Rui Manuel Reis, Rui Manuel Reis, Rui Manuel Reis, Valtencir Zucolotto   +12 more
doaj   +1 more source

Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children

Environmental Health, 2021
Background Asthma represents a syndrome for which our understanding of the molecular processes underlying discrete sub-diseases (i.e., endotypes), beyond atopic asthma, is limited.
Hyunok Choi, Miroslav Dostal, Anna Pastorkova, Pavel Rossner, Radim J. Sram   +4 more
doaj   +1 more source

Applied Nanotoxicology [PDF]

International Journal of Toxicology, 2016
Nanomaterials, including nanoparticles and nanoobjects, are being incorporated into everyday products at an increasing rate. These products include consumer products of interest to toxicologists such as pharmaceuticals, cosmetics, food, food packaging, household products, and so on. The manufacturing of products containing or utilizing nanomaterials in
David W, Hobson, Stephen M, Roberts, Anna A, Shvedova, David B, Warheit, Georgia K, Hinkley, Robin C, Guy   +5 more
openaire   +2 more sources

Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat

Particle and Fibre Toxicology, 2020
Background Multi-walled carbon nanotubes can be divided into two general subtypes: tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80–90 nm in diameter) are straight-type MWCNTs, and similarly to asbestos, both are carcinogenic to the lung
Dina Mourad Saleh, William T. Alexander, Takamasa Numano, Omnia Hosny Mohamed Ahmed, Sivagami Gunasekaran, David B. Alexander, Mohamed Abdelgied, Ahmed M. El-Gazzar, Hiroshi Takase, Jiegou Xu, Aya Naiki-Ito, Satoru Takahashi, Akihiko Hirose, Makoto Ohnishi, Jun Kanno, Hiroyuki Tsuda   +15 more
doaj   +1 more source

Nanomaterials and security in occupational and forensic medicine: insights from nanotoxicology [PDF]

Frontiers in Toxicology
Tran L, Treglia M, Coppeta L, Ferrari C, Pallocci M, Campagnolo L, De Miranda Junior LC, Piccoli B, Gaskin S, Cortes Fernandes F, Dantas Filho F, Passalacqua P, Pietroiusti A, Ippoliti L, Bragaglia M, Nanni F, Magrini A, Marsella LT.   +17 more
exaly   +2 more sources

Mesenchymal Stem Cell-Based Therapy for Retinal Degenerative Diseases: Experimental Models and Clinical Trials

Cells, 2021
Retinal degenerative diseases, such as age-related macular degeneration, retinitis pigmentosa, diabetic retinopathy or glaucoma, represent the main causes of a decreased quality of vision or even blindness worldwide. However, despite considerable efforts,
Vladimir Holan, Katerina Palacka, Barbora Hermankova   +2 more
doaj   +1 more source

Toxicities of synthesized green iron oxide nanoparticles on Trialeurodes vaporariorum and their effects on antioxidant enzymes and lipid peroxidation [PDF]

نامه انجمن حشره‌شناسی ایران, 2023
In this study, lethal concentrations of iron-oxide nanoparticles (FeONPs) synthesized from plants (alfalfa, basil, eucalyptus, cinnamon) were investigated for their effects on mortality, antioxidant enzyme activities (superoxide dismutase (SOD), catalase
Najmeh Sahebzadeh, Tayebeh Haddadi, Azizollah Mokhtari   +2 more
doaj   +1 more source

Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study

Particle and Fibre Toxicology, 2022
Background Considering the expanding industrial applications of carbon nanotubes (CNTs), safety assessment of these materials is far less than needed. Very few long-term in vivo studies have been carried out.
Dina Mourad Saleh, Shengyong Luo, Omnia Hosny Mohamed Ahmed, David B. Alexander, William T. Alexander, Sivagami Gunasekaran, Ahmed M. El-Gazzar, Mohamed Abdelgied, Takamasa Numano, Hiroshi Takase, Makoto Ohnishi, Susumu Tomono, Randa Hussein Abd el Hady, Katsumi Fukamachi, Jun Kanno, Akihiko Hirose, Jiegou Xu, Shugo Suzuki, Aya Naiki-Ito, Satoru Takahashi, Hiroyuki Tsuda   +20 more
doaj   +1 more source

Advances in Nanotoxicology: Towards Enhanced Environmental and Physiological Relevance and Molecular Mechanisms

Nanomaterials, 2021
Nanotoxicology, a discipline transpired by the need to assess the human and environmental safety of nanoscale materials, has evolved over the past 15 years into a mature area of toxicology [...]
Anne Kahru, Monika Mortimer
doaj   +1 more source

TiO2 nanoparticles alter nutrients acquisition, growth, biomacromolecules, oil composition and modulate antioxidant defense system in Mentha arvensis L.

Plant Nano Biology, 2023
The current study demonstrates the impact of TiO2 NPs (0–5 µg ml−1) on Mentha arvensis L. (Lamiaceae) cultivated commercially for essential oil. The high concentration of titanium in plant tissues (roots, leaves and stem), presence of Ti peaks in EDS of ...
Subodh Kumar, Archana Dwivedi, Alok Kumar Pandey, Poornima Vajpayee   +3 more
doaj   +1 more source