A colloidal singularity reveals the crucial role of colloidal stability for nanomaterials in-vitro toxicity testing: nZVI-microalgae colloidal system as a case study. [PDF]
PLoS ONE, 2014 Aggregation raises attention in Nanotoxicology due to its methodological implications. Aggregation is a physical symptom of a more general physicochemical condition of colloidal particles, namely, colloidal stability.
Soledad Gonzalo +8 more
doaj +1 more source
Mechanism of cellular uptake of genotoxic silica nanoparticles. [PDF]
, 2012 Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of uptake of amorphous silica nanoparticles of 14 nm diameter, which agglomerate in culture medium ...
Brown, AP +5 more
core +3 more sources
Informing Selection of Nanomaterial Concentrations for ToxCast In Vitro Testing based on Occupational Exposure Potential [PDF]
, 2011 Background: Little justification is generally provided for selection of in vitro assay testing concentrations for engineered nanomaterials (ENMs). Selection of concentration levels for hazard evaluation based on real-world exposure scenarios is desirable.
Gangwal, Sumit +6 more
core +1 more source
Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung [PDF]
, 2010 With the rapid spread of carbon nanotubes (CNTs) applications, the respiratory toxicity of these compounds has attracted the attention of many scientists. Several studies have reported that after lung administration, CNTs could induce granuloma, fibrosis,
Arnaud, R. +7 more
core +1 more source
Particle and Fibre Toxicology, 2017 Background Engineered nanomaterials (ENMs) are increasingly added to foods to improve their quality, sensory appeal, safety and shelf-life. Human exposure to these ingested ENMs (iENMS) is inevitable, yet little is known of their hazards.
Glen M. DeLoid +12 more
doaj +1 more source
Safety of Gold Nanoparticles: From In Vitro to In Vivo Testing Array Checklist
Pharmaceutics, 2023 In recent years, gold nanoparticles (AuNPs) have aroused the interest of many researchers due to their unique physicochemical and optical properties.
Joana Lopes +11 more
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Cytotoxicity in the Age of Nano: The Role of Fourth Period Transition Metal Oxide Nanoparticle Physicochemical Properties [PDF]
, 2013 A clear understanding of physicochemical factors governing nanoparticle toxicity is still in its infancy. We used a systematic approach to delineate physicochemical properties of nanoparticles that govern cytotoxicity.
Aronstam, Robert S. +7 more
core +2 more sources
Biological impact assessment of nanomaterial used in nanomedicine. introduction to the NanoTEST project. [PDF]
, 2015 Therapeutic nanoparticles (NPs) are used in nanomedicine as drug carriers or imaging agents, providing increased selectivity/specificity for diseased tissues.
Collins, AR +6 more
core +2 more sources
Effects of food-borne nanomaterials on gastrointestinal tissues and microbiota [PDF]
, 2017 Ingestion of engineered nanomaterials is inevitable due to their addition to food and prevalence in food packaging and domestic products such as toothpaste and sun cream.
Bouwmeester, Hans +2 more
core +5 more sources
Particle and Fibre Toxicology, 2009 In vitro studies with particles are a major staple of particle toxicology, generally used to investigate mechanisms and better understand the molecular events underlying cellular effects. However, there is ethical and financial pressure in nanotoxicology,
Gulumian Mary +3 more
doaj +1 more source