Results 131 to 140 of about 9,718 (271)

Nanozymes for the Therapeutic Treatment of Diabetic Foot Ulcers [PDF]

Diabetic foot ulcers (DFU) are chronic, refractory wounds caused by diabetic neuropathy, vascular disease, and bacterial infection, and have become one of the most serious and persistent complications of diabetes mellitus because of their high incidence ...
Chen, Shaowei, DuBois, Davida Briana, Liu, Qiming, Xiao, Xueqian, Yao, Qunfeng, Zhang, Guo-Jun, Zhang, Yu Lin, Zhao, Fei   +7 more
core   +1 more source

Oxidative stress in disease and aging: Mechanisms and therapies [PDF]

, 2015
Cabello-Verrugio, Claudio, Mosqueira, Matías, Ruiz-Ortega, Marta, Simón, Felipe   +3 more
core   +3 more sources

Metal-phenolic nanozyme as a ferroptosis inhibitor for alleviating cisplatin-induced acute kidney injury

Frontiers in Pharmacology
IntroductionCisplatin-induced acute kidney injury (AKI) is primarily caused by oxidative stress from reactive oxygen species (ROS) accumulation. Developing ROS scavengers presents promising opportunities for preventing and treating this condition by ...
Yunfeng Xiong, Huimin Kang, Yanping Rao, Xiayu Huang, Yang Zhu, Lixin Wei, Lixin Wei   +6 more
doaj   +1 more source

Therapeutic Frontiers in Nanozyme-Based Cancer Treatment: Advances, Challenges, and Future Directions [PDF]

Nanozymes, artificial nanomaterials mimicking enzyme activity, are at the forefront of innovative cancer therapies, particularly in chemodynamic therapy (CDT), photodynamic therapy (PDT), and photothermal therapy (PTT).
A.I. Kuruppu, D.M. Silva
core   +2 more sources

A Multifunctional Nanozyme Hydrogel with Antibacterial, Antioxidative, and Photo-Induced Nitric Oxide-Supplying Properties for Promoting Infected Wound Healing

Pharmaceutics
Objectives: To design a multifunctional nanozyme hydrogel with antibacterial, photo-responsive nitric oxide-releasing, and antioxidative properties for promoting the healing of infected wounds. Methods: We first developed ultra-small silver nanoparticles
Wen Zuo, Kunpeng Wei, Xinyi Zhang, Dongjing Wang, Haoyang Gong, Yanzhuo Zhang, Hui Wang   +6 more
doaj   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

H2O2 Self-Supplied MoS2/CaO2 Nanozyme Hydrogel with Near-Infrared Photothermal Synergetic Cascade Peroxidase-Like Activity for Wound Disinfection [PDF]

In wound healing and clinical anti‐infection therapy, the current feasibility of nanocatalysts is extremely limited because of inadequate reactive oxygen species (ROS) generation.
Chen, Linjie, Gong, Zehua, He, Zhimin, Huang, Jinyi, Li, Huaqiong, Ou, Yujie, Peng, Ke, Ullah, Ihsan, Wu, Aimin, Yin, Wenyan   +9 more
core   +2 more sources

Kartogenin‐Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme‐Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration

Small Structures
Articular cartilage defects remain an intractable clinical challenge due to the limited capacity of cartilage for self‐renewal and repair. Excessive accumulation of reactive oxygen species (ROS) leads to mitochondrial dysfunction, inflammation, and ...
Shu‐Hang He, Zhi‐Han Shen, Ren Zhang, Po‐Lin Liu, Xu‐Ran Li, Qing‐Song Deng, Yu‐Chen Zhang, Ang Wang, Xiao‐Qiu Dou, Shang‐Chun Guo, Shi‐Cong Tao   +10 more
doaj   +1 more source

Smartphone-enhanced nanozyme sensors: Colorimetric and fluorescence sensing techniques

Biosensors and Bioelectronics: X
The advent of smartphone technology has changed the biosensing field, especially by integrating nanozyme-based colorimetric, fluorescence sensing strategy.
Tileshwar Sahare, Nandini Singh, Badri Narayana Sahoo, Abhijeet Joshi   +3 more
doaj   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source