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Hydrolytic Nanozymes

European Journal of Organic Chemistry, 2020
In 2004 we first reported catalytic nanoparticles, that are able to cleave phosphate diesters with very high efficiency (Angew. Chem. Int Ed, 2004, 43, 6165–6169) and dubbed them “nanozymes” for the similarity of their behavior with natural enzymes, both in terms of efficiency and mechanism of action.
Gabrielli L.   +4 more
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Nanozymes for Regenerative Medicine

Small Methods, 2022
AbstractNanozymes refer to nanomaterials that catalyze enzyme substrates into products under relevant physiological conditions following enzyme kinetics. Compared to natural enzymes, nanozymes possess the characteristics of higher stability, easier preparation, and lower cost.
Xiaozhou Mou   +8 more
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Cleaving DNA by nanozymes

Journal of Materials Chemistry B, 2020
Various nanomaterials can mimic the activities of nucleases for hydrolytic and oxidative DNA cleavage on different sites allowing interesting biomedical and bioanalytical applications.
Ruiqin Fang, Juewen Liu
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Nanozyme‐based luminescence detection

Luminescence, 2020
AbstractNanozymes refer to nanomaterial‐based enzyme mimics. Most nanozyme assays use chromogenic molecules as substrates that can produce an absorbance change in the visible region upon reaction. For certain applications, such as imaging, fluorescence and luminescence signals are required.
Jinyi Zhang, Juewen Liu
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Catalytic Nanozyme for Radiation Protection

Bioconjugate Chemistry, 2021
Radiotherapy has been widely used in clinical cancer treatment. However, the ionizing radiation required to kill the tumor will inevitably cause damage to the surrounding normal tissues. To minimize the radiation damage and side effects, small molecular radioprotective agents have been used as clinical adjuvants for radiation protection of healthy ...
Ruiying Zhao   +4 more
openaire   +2 more sources

Defect‐Engineered Nanozyme‐Linked Receptors

Small, 2021
AbstractThough nanozymes are successfully applied in various areas, the increasing demands facilitate the exploitation of nanozymes possessing higher activity and more functions. Natural enzyme‐linked receptors (ELRs) are critical components for signal transductions in vivo by expressing activity variations after binding with ligands. Inspired by this,
Yu Wu   +13 more
openaire   +2 more sources

Nanozymes: Functional Nanoparticle‐Based Catalysts

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
PASQUATO, LUCIA   +2 more
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Catalytic antimicrobial therapy using nanozymes

WIREs Nanomedicine and Nanobiotechnology, 2021
AbstractNanozymes are nanomaterials with enzyme‐like characteristics, which catalyze the conversion of enzyme substrates and follow enzymatic kinetics under physiological conditions. As a new generation of artificial enzymes, nanozymes provide alternative approaches for those upon enzymatic catalysis.
Qian Wang, Jing Jiang, Lizeng Gao
openaire   +2 more sources

Nanozyme-Based Enhanced Cancer Immunotherapy

Tissue Engineering and Regenerative Medicine, 2022
Catalytic nanoparticles with natural enzyme-mimicking properties, known as nanozymes, have emerged as excellent candidate materials for cancer immunotherapy. Owing to their enzymatic activities, artificial nanozymes not only serve as responsive carriers to load drugs and therapeutic molecules for cancer treatment, but also act as enzymes for modulating
Ngoc Man Phan   +2 more
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Nanozymes for Therapeutics

2020
Free radicals (ROS, NOS, etc.) play a vital role in the pathological process of many diseases from nerve and organ injury to cancer, tissue damage, and inflammatory disorders. Though moderate amount of free radicals helps maintain the normal body function and hamper the growth of bacteria, excessive amount of radicals will induce oxidative stress ...
Wen Cao   +3 more
openaire   +1 more source

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