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Naomi Wray [PDF]

open access: bronzeNeuron, 2023
Naomi Wray works at the interface of genetics, statistics and psychiatric disorders. With early training in quantitative genetics applied to livestock she brought to the field a perspective on the polygenic nature of common, complex disease. She advocates for experimental paradigms that exploit polygenicity to advance translational outcomes in ...
Naomi R. Wray
exaly   +4 more sources

Ruth 1:1–5 read in the context of challenges of the migration of Nigerians

open access: yesVerbum et Ecclesia, 2023
This study used Ruth 1:1–5 as a lens in the study of the increasing challenges Nigerian migrants face. Famine was ravaging the land, and hence Elimelech moved his family away from Israel to the country of Moab so they would be fed (Rt 1:1–2).
Damian O. Odo, Favour C. Uroko
doaj   +1 more source

Arketipe Kepribadian Naomi: Suatu Kajian Psikoanalitikal Carl Gustav Jung

open access: yesGema Teologika, 2022
Naomi is one of the characters in the book of Ruth who experiences many challenges. The death of her husband and two sons left Naomi as a widow. Naomi has to survive with the status as a widow who has limitations in social circles.
Feliana Eliza Kasemetan   +2 more
doaj   +1 more source

Uncoupling Lipid Synthesis from Adipocyte Development

open access: yesBiomedicines, 2023
Obesity results from the expansion of adipose tissue, a versatile tissue regulating energy homeostasis, adipokine secretion, thermogenesis, and inflammation. The primary function of adipocytes is thought to be lipid storage through lipid synthesis, which
Qianfen Wan   +3 more
doaj   +1 more source

Single-agent FOXO1 inhibition normalizes glycemia and induces gut β-like cells in streptozotocin-diabetic mice

open access: yesMolecular Metabolism, 2022
Objectives: Insulin treatment remains the sole effective intervention for Type 1 Diabetes. Here, we investigated the therapeutic potential of converting intestinal epithelial cells to insulin-producing, glucose-responsive β-like cells by targeted ...
Yun-Kyoung Lee   +8 more
doaj   +1 more source

Analyzing The Grief of Naomi in The Book of Ruth

open access: yesDunamis: Jurnal Teologi dan Pendidikan Kristiani, 2022
This article analyzed the grief of Naomi in the book of Ruth by using the six stages of grief by Elisabeth Kübler-Ross and David Kessler. Although Naomi could be an inadequate model in dealing with her grief, her attitude resonates with many people in ...
Sia Kok Sin
doaj   +1 more source

PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction

open access: yesCells, 2023
Aging and obesity are the two prominent driving forces of metabolic dysfunction, yet the common underlying mechanisms remain elusive. PPARγ, a central metabolic regulator and primary drug target combatting insulin resistance, is hyperacetylated in both ...
Ying He   +6 more
doaj   +1 more source

FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice

open access: yesMolecular Metabolism, 2021
Objective: Forkhead box protein O1 (FOXO1) plays a key role in regulating hepatic glucose production, but investigations of FOXO1 inhibition as a potential therapeutic approach have been hampered by a lack of selective chemical inhibitors.
Yun-Kyoung Lee   +7 more
doaj   +1 more source

The message of the book Ruth: A reflection on Naomi’s traumatic journey to Mara and back

open access: yesIn die Skriflig, 2020
The book of Ruth is generally regarded as centring on the key figure of Ruth. It is claimed that this limits the narrative, influencing the interpretation.
Raymond Potgieter, Hermanus Taute
doaj   +1 more source

Rearing mice at 22°C programs increased capacity to respond to chronic exposure to cold but not high fat diet

open access: yesMolecular Metabolism, 2023
Objective: Rodent models raised at environmental temperatures of 21–22 °C are increasingly switched to thermoneutral housing conditions in adulthood to better capture human physiology. We quantified the developmental effects of rearing mice at an ambient
Daniele Neri   +4 more
doaj   +1 more source

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