Results 121 to 130 of about 45,887 (257)

O2‐Mediated Cu‐Catalyzed Dehydrogenative Sulfilimination of Tyrosines and Bioactive Phenols

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
We report herein the mild O2‐mediated Cu‐catalyzed dehydrogenative sulfilimination of diverse bioactive phenols with simple sulfenamides. The bioconjugation of unmodified native peptides, in particular at their tyrosine units with the dehydrogenative phenochalcogenazination reaction, has attracted much attention lately due to potential click type ...
Fang Xiao, Frederic W. Patureau
wiley   +1 more source

Catalytic Enantioselective Synthesis of Conformationally Stable C(sp2)−C(sp3) Naphthocoumarin Atropisomers

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
The enantioselective synthesis of naphthocoumarin adducts via a tandem organocatalytic 1,4‐addition/decarboxylation delivers excellent control over a newly forged stereocenter and yields configurationally stable synclinal atropisomers. The process features broad substrate scope and scalability, and its structural and mechanistic foundations are ...
M. Chiara Cabua, Davide Moi, Emanuele Cocco, Valentina Onnis, Enrico Podda, David J. Aitken, Armando Carlone, Renzo Luisi, Enrica Tuveri, Drew F. Parsons, Francesco Secci   +10 more
wiley   +1 more source

Targeting CDK6 and BCL2 Exploits the MYB Addiction of Ph+ Acute Lymphoblastic Leukemia [PDF]

, 2018
Philadelphia chromosome–positive acute lymphoblastic leukemia (Phþ ALL) is currently treated with BCR-ABL1 tyrosine kinase inhibitors (TKI) in combination with chemotherapy. However, most patients develop resistance to TKI through BCR-ABL1–dependent and –
Addya, Sankar, Calabretta, Bruno, De Dominici, Marco, Ferrari, Anna, Fortina, Paolo, Iacobucci, Ilaria, Mariani, Samanta A., Martinelli, Giovanni, Peterson, Luke F., Porazzi, Patrizia, Rambaldi, Alessandro, Soliera, Angela Rachele, Spinelli, Orietta   +12 more
core   +1 more source

Electrochemical Detection of Thrombin Activity Using an Electrogenic Substrate: Toward Rapid Coagulation Monitoring

ChemElectroChem, Volume 13, Issue 9, 5 May 2026.
Measuring thrombin activity provides critical information about coagulation health. A voltammetry technique was developed to monitor thrombin activity rapidly on a screen‐printed gold electrode. Thrombin selectively cleaves the bond between para‐nitroaniline (pNA) and a tri‐peptide substrate. pNA cleavage is monitored electrochemically by measuring its
Sina Ardalan, Anna Ignaszak
wiley   +1 more source

Dearomatization with Axial‐to‐Central Chirality Conversion

European Journal of Organic Chemistry, Volume 29, Issue 17, 5 May 2026.
Atropisomers are exciting synthetic targets with unique properties, which find applications in many fields of chemistry. However, considering them as substrates is not very frequent, notably in the context of dearomatization reaction. We wish to discuss the different strategies for the dearomatization of aromatic atropisomers with axial‐to‐central ...
Morgane Mando, Clément Lemaitre, Thierry Constantieux, Xavier Bugaut   +3 more
wiley   +1 more source

TOXICITY AND LC50 DETERMINATION OF PHENOL AND 1-NAPHTOL IN CASPIAN KUTUM AND BREAM FINGERLINGS

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2003
In this investigation acute toxicity of phenol and 1-naphthol were determined based on OECD guideline in the laboratory. Experimental fishes were Caspian kutum (Rutilus frisii kutum) and bream (Abramis brama orientalis).
F. Shariyati1; A. Esmaeili sari2; M. Piri3
doaj  

A Biochar‐Based Composite Hydrogel Microenvironment for Enhanced Biocatalysis

Advanced Materials, Volume 38, Issue 26, 8 May 2026.
This work presents the synthesis of a polyacrylamide hydrogel wherein biomass‐derived biochar is co‐encapsulated with the enzyme horseradish peroxidase (HRP). The resulting composite hydrogel possesses balanced electron‐rich and electron‐deficient domains, creating an optimal microenvironment that concentrates both hydrogen peroxide and phenol ...
Shengzhe Wang, Jingling Zhu, Weiyang Xue, Yuting Wen, Zhongxing Zhang, Xia Song, Yuan Yu, Chenglin Sun, Huangzhao Wei, Jun Li   +9 more
wiley   +1 more source

Construction of a dinuclear silver(I) coordination complex with a Schiff base containing 4-amino-1,2,4-triazole ligands

Acta Crystallographica Section E, 2009
The new ligand 1-(1,2,4-triazol-4-yliminomethyl)-2-naphthol (L) and the title silver(I) complex, namely bis[μ-1-(1,2,4-triazol-4-yliminomethyl)-2-naphthol]bis{[1-(1,2,4-triazol-4-yliminomethyl)-2-naphthol]silver(I)} dinitrate monohydrate, [Ag2 ...
doaj   +1 more source

Multi‐Level Confinement Single‐Molecule Charge Transfer Activated PRET for Near‐Infrared Targeted Cell Imaging

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The cascade supramolecular assembly of charge‐transfer arrays not only triggered a topological transformation from nanofiber to nanorod and vesicles, but also promoted single‐molecule phosphorescent resonance energy transfer, expanding phosphorescence emission at 500 nm to near‐infrared delayed fluorescence emission at 650 nm with a lifetime of 11.20 ...
Zhuo Lei, Sai Li, Pei‐Ao Sun, Yong Chen, Xuejian Zhang, Yu Liu   +5 more
wiley   +1 more source

Synthesis, Characterisation and biological activity for binuclear complexes with Co(II), Cu(II) and Zn(II) with new ligand m-phenylendi(azo-2-naphthol) ligand type N2O2.

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
   In this work, the(m-phenylenediamine) and (2-naphthol) have been used in the synthesis of tetradentate ligand [m-phenylenedi(azo-2-naphthol)][H2L] type (N2O2).
W. A. J. Al-Saedi
doaj