Results 71 to 80 of about 6,879 (216)

Biosynthesis of food constituents: Natural pigments: Part 1

Czech Journal of Food Sciences, 2007
This review article gives a survey of the generally accepted biosynthetic pathways that lead to the most important natural pigments in organisms closely related to foods and feeds.
Jan Velíšek, Jiří Davídek, Karel Cejpek   +2 more
doaj   +1 more source

Synthesis of 5,8-Dihydroxy-2-methoxy-1,4-naphthoquinone Derivatives. A Major Naphthoquinone Moiety of Some of Naphthoquinone Antibiotics [PDF]

Bulletin of the Chemical Society of Japan, 1987
Abstract 6-Formyl- and 6-hydroxymethyl-5,8-dihydroxy-2-methoxy-1,4-naphthoquinones were, respectively, prepared from 2-formyl- and 2-hydroxymethyl-1,4,5,6,8-pentamethoxynaphthalenes which were synthesized as key intermediates of the new antibiotics containing 2-methoxynaphthazarin structure.
Yasuhiro Tanoue, Akira Terada, Toshiyuki Tsuboi, Takayuki Hayashida, Otohiko Tsuge   +4 more
openaire   +1 more source

PLS-Prediction and Confirmation of Hydrojuglone Glucoside as the Antitrypanosomal Constituent of Juglans Spp.

Molecules, 2015
Naphthoquinones (NQs) occur naturally in a large variety of plants. Several NQs are highly active against protozoans, amongst them the causative pathogens of neglected tropical diseases such as human African trypanosomiasis (sleeping sickness), Chagas ...
Therese Ellendorff, Reto Brun, Marcel Kaiser, Jandirk Sendker, Thomas J. Schmidt   +4 more
doaj   +1 more source

Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2′-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment

Molecules, 2018
Epoxymethoxylawsone is a naphthoquinone derivative promising as drug candidate for the treatment of leishmaniases. In the present work the effectiveness of epoxymethoxylawsone, and meglumine antimoniate on Leishmania (Leishmania) amazonensis parasites ...
Luiz Filipe Gonçalves Oliveira, Franklin Souza-Silva, Luzia Monteiro de Castro Côrtes, Lea Cysne-Finkelstein, Mirian Cláudia de Souza Pereira, Francisco Odêncio de Oliveira Junior, Rosa Teixeira Pinho, Suzana Corte Real, Saulo Cabral Bourguignon, Vitor Francisco Ferreira, Carlos Roberto Alves   +10 more
doaj   +1 more source

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

A new route to naphtho[2,3-b]furan-4,9-diones from thio-substituted 1,4-naphthoquinones [PDF]

, 1990
Reaction of 2-phenylthio- or 2-ethylthio-1,4-naphthoquinones (1) and (2) with lithium enolates or pyridinium ylides was found to give alkylated 1,4-naphthoquinones (3)-(6) in high yields.
Toru, Takeshi, Sekiya, Takashi, Kang, Wen Bing, Ueno, Yoshio   +3 more
core   +1 more source

Reaction Mechanisms of H₂S Oxidation by Naphthoquinones

Antioxidants
1,4-naphthoquinones (NQs) catalytically oxidize H2S to per- and polysufides and sulfoxides, reduce oxygen to superoxide and hydrogen peroxide, and can form NQ-SH adducts through Michael addition.
Kenneth R. Olson, Kasey J. Clear, Tsuyoshi Takata, Yan Gao, Zhilin Ma, Ella Pfaff, Anthony Travlos, Jennifer Luu, Katherine Wilson, Zachary Joseph, Ian Kyle, Stephen M. Kasko, Prentiss Jones Jr, Jon Fukuto, Ming Xian, Gang Wu, Karl D. Straub   +16 more
doaj   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, Volume 40, Issue 7, Page 4611-4637, July 2026.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Autocatalytic Deprotection of Diboronate‐Protected Quinones via Redox Cross‐Catalysis: Mechanistic Insights Into Double Masking Strategies

ChemSystemsChem, Volume 8, Issue 4, July 2026.
Mechanistic insights and design principles of diprotected molecular probes for autocatalytic redox amplification systems: assessing the influence of molecular structure symmetry and electronic substituent effects on the double deprotection and autocatalytic response. ABSTRACT We report an autocatalytic molecular amplification system based on the double
Pan Hui, Alexandra Pastor, Mathieu Branca, Benoît Limoges, François Mavré   +4 more
wiley   +1 more source