Results 141 to 150 of about 58,835 (270)
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss +8 more
wiley +1 more source
Pain Management in Aneurysmatic Subarachnoid Haemorrhage: A Survey of Nordic Physicians
ABSTRACT Background Headache caused by aneurysmatic subarachnoid hemorrhage (aSAH) is often severe and may persist long after the ictus. Pharmacological pain management can be challenging due to poor efficacy or adverse effects. Multimodal pharmacotherapy is often required. Lack of guidelines and good quality clinical studies on pain management has led
Hanna Sariola +14 more
wiley +1 more source
Abstract Background Previous observational studies have reported an increased risk of venous thromboembolism (VTE) among non‐steroidal anti‐inflammatory drug (NSAID) users compared with non‐users. However, these studies may have been subject to bias due to unmeasured confounders related to patient conditions requiring NSAIDs.
Yuichiro Matsuo +2 more
wiley +1 more source
Aspirin and glyceryl trinitrate effects on polyamine uptake and smooth muscle cell growth [PDF]
This paper looks at aspirin and glyceryl trinitrate effects on polyamine uptake and smooth muscle cell ...
Clarke, Brendan +4 more
core
A four‐component synthesis of azetidines with an all‐carbon quaternary center via strain‐release 1,3‐bis‐carbofunctionalization of 1‐azabicyclobutanes (ABB) is described. Each reaction component can be modified to permit a high‐throughput‐like library preparation, producing azetidines with various appendages, including biorelevant molecules.
Yi‐Hua Lee +10 more
wiley +1 more source
A Riboflavin‐Derived Flavinium Salt Mediates Chemoselective Methylation Reactions
A two‐component methylation protocol was developed, where the active flavin mediator can be recycled in a single step. Crystallographic data and NMR spectroscopy support the mechanistic proposal, while chemoselective methylation was observed for a broad range of biologically relevant substrates. ABSTRACT Selective methylation is among the most relevant
Tim Langschwager +3 more
wiley +1 more source
NICEly does it: economic analysis within evidence-based clinical practice guidelines [PDF]
There is increasing professional and policy interest in the role of clinical guidelines for promoting effective and efficient health care. The NHS Health Technology Assessment Programme identified an urgent need, when such guidelines are produced, to ...
James Mason +3 more
core
A bench‐stable saccharin electrophilic reagent enables the direct installation of the heptafluoroisopropylthio group onto diverse (hetero)arenes and amines under mild conditions. The method forms CSRF and NSRF bonds in a single step and allows subsequent oxidation to sulfonamides.
Javier Jaureguizar +4 more
wiley +1 more source

