Results 11 to 20 of about 58,835 (270)

Fabrication and Characterizations of Pharmaceutical Emulgel Co-Loaded with Naproxen-Eugenol for Improved Analgesic and Anti-Inflammatory Effects

open access: yesGels, 2022
The aim of this study was to fabricate and characterize a pharmaceutical emulgel co-loaded with naproxen/eugenol for transdermal delivery to improve the analgesic and anti-inflammatory effects and to eliminate GIT adverse reactions.
Barkat Ali Khan   +9 more
doaj   +2 more sources

Mesoporous Silica as a Drug Delivery System for Naproxen: Influence of Surface Functionalization

open access: yesMolecules, 2020
In this work we describe the relationship between surface modification of hexagonally ordered mesoporous silica SBA-15 and loading/release characteristics of nonsteroidal anti-inflammatory drug (NSAID) naproxen.
Lukáš Žid   +8 more
doaj   +2 more sources

Anti-metastatic Properties of Naproxen-HBTA in a Murine Model of Cutaneous Melanoma

open access: yesFrontiers in Pharmacology, 2019
The beneficial effects of H2S-release and of COXs-inhibition have been exploited in the design of novel anti-inflammatory drugs, the H2S-releasing non-steroidal anti-inflammatory drugs (H2S-NSAIDs), showing promising potential for chemoprevention in ...
Giuseppe Ercolano   +12 more
doaj   +2 more sources

Intrauterine lidocaine and naproxen for analgesia during intrauterine device insertion: randomized controlled trial

open access: yesContraception and Reproductive Medicine, 2019
Background This study evaluates oral naproxen and intrauterine instillation of lidocaine for analgesia with intrauterine device (IUD) placement as compared to placebo. Methods This was a randomized, double-blind, placebo-controlled trial.
Shana M. Miles   +2 more
doaj   +2 more sources

Computational Design, Synthesis, and Pharmacological Evaluation of Naproxen-Guaiacol Chimera for Gastro-Sparing Anti-Inflammatory Response by Selective COX2 Inhibition

open access: yesMolecules, 2022
The 4-allyl guaiacol is a natural phenolic molecule that has been widely studied for its antioxidant capacity against reactive-oxygen-species-mediated cellular damage.
P. Shinu   +14 more
semanticscholar   +1 more source

TiO2-La2O3 as Photocatalysts in the Degradation of Naproxen

open access: yesInorganics, 2022
The indiscriminate use of naproxen as an anti-inflammatory has been the leading cause of pollution in sewage effluents. Conversely, titanium dioxide is one of the most promising photocatalyst for the degradation of pollutants.
Adriana Marizcal-Barba   +7 more
semanticscholar   +1 more source

Recent Advances in the Synthesis of Ibuprofen and Naproxen

open access: yesMolecules, 2021
Herein, we review the recent progress in the synthesis of representative nonsteroidal anti-inflammatory drugs (NSAIDs), ibuprofen and naproxen. Although these drugs were discovered over 50 years ago, novel practical and asymmetric approaches are still ...
M. Ha, Seung-Mann Paek
semanticscholar   +1 more source

Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies

open access: yesPharmaceuticals, 2021
A library of novel naproxen based 1,3,4-oxadiazole derivatives (8–16 and 19–26) has been synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized hybrids, compound2-(4-((5-((S)-1-(2-methoxynaphthalen-6-yl)ethyl)-1,3,4-oxadiazol-
Mohammad Mahboob Alam   +9 more
semanticscholar   +1 more source

Naproxen in the environment: its occurrence, toxicity to nontarget organisms and biodegradation

open access: yesApplied Microbiology and Biotechnology, 2020
This article summarizes the current knowledge about the presence of naproxen in the environment, its toxicity to nontarget organisms and the microbial degradation of this drug.
D. Wojcieszyńska, U. Guzik
semanticscholar   +1 more source

Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus

open access: yesMolecules, 2021
There is an urgent need for specific antiviral treatments directed against SARS-CoV-2 to prevent the most severe forms of COVID-19. By drug repurposing, affordable therapeutics could be supplied worldwide in the present pandemic context.
O. Terrier   +15 more
semanticscholar   +1 more source

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