Results 11 to 20 of about 28,358 (239)

Conjugation And Evaluation of Novel Polymeric Naproxen-PEG Esters [PDF]

, 2023
Nonsteroidal anti-inflammatory drugs (NSAID) are commonly used and prescribed across the globe. A defining characteristic of NSAIDs is their poor water solubility; therefore, in a practical setting this translates directly to poor systemic absorption in ...
Syon, Schlecht, Haley , Fleming, Christina, Curtis, Christina Curtis, Syon Schlecht, Haley Fleming   +5 more
core   +1 more source

The improved photostability of naproxen in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]

Hemijska Industrija, 2015
The aim of this work was the preparation of the inclusion complex of naproxen with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) in order to improve the physical and chemical properties of naproxen.
Ilić-Stojanović Snežana S., Nikolić Vesna D., Nikolić Ljubiša B., Zdravković Aleksandar S., Kapor Agneš J., Popsavin Mirjana M., Petrović Slobodan D.   +6 more
doaj   +1 more source

Evaluation of physicochemical, in vivo analgesic and antiinflammatory activities of Brachystegia eurycoma gum-based naproxen loaded niosomal gels

German Journal of Pharmaceuticals and Biomaterials, 2023
Protracted oral Naproxen administration for acute and chronic conditions, such as rheumatoid arthritis treatment, may cause peptic ulcers. The topical application of Naproxen will circumvent this effect.
Sinodukoo Eziuzo Okafo, John Ikechi Ordu, Godfrey Ofagbor, Emmanuel Agbamu   +3 more
doaj   +1 more source

Supercritical fluid impregnation of naproxen into mesoporous SiO2 SBA-15

, 2023
Naproxen was impregnated into mesoporous SiO2 SBA-15 using the Supercritical Solution Impregnation (SSI) technique. Experiments were performed at 50–70ºC and 15–25 MPa in pure CO2 and CO2 modified with ethanol, ethyl acetate and menthol.
Pérez Velilla, Eduardo, Cabañas Poveda, Albertina, Pepczynska, Marzena, Calvo Garrido, María Lourdes, González, Juan   +4 more
core   +1 more source

Efficacy of EGFR Inhibitors and NSAIDs Against Basal Bladder Cancers in a Rat Model: Daily vs. Weekly Dosing, Combining EGFR Inhibitors with Naproxen, and Effects on RNA Expression

Bladder Cancer, 2021
BACKGROUND: There are few effective treatments specifically aimed at basal bladder cancer. OBJECTIVE: Female F344 rats administered N-butyl-N-(4-hydroxybutyl)-nitrosamine (OH-BBN) develop large invasive bladder cancers.
Ronald A. Lubet, Amit Kumar, Jennifer T. Fox, Ming You, Altaf Mohammed, M. Margaret Juliana, Clinton J. Grubbs   +6 more
doaj   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Enantioselective hydrolysis of racemic naproxen nitrile and naproxen amide to S-naproxen by new bacterial isolates [PDF]

, 1994
Bacteria were enriched from soil samples with succinate as a carbon source and racemic naproxen nitrile [2-(6-methoxy-2-naphthyl)propionitrile] as sole source of nitrogen.
Böhme, Joachim, Knackmuss, Hans-Joachim, Effenberger, Franz, Layh, Norman, Stolz, Andreas   +4 more
core   +1 more source

A detailed in vitro study of naproxen metal complexes in quest of new therapeutic possibilities

Alexandria Journal of Medicine, 2017
Objective: The present study was designed to investigate the in vitro anti-inflammatory, antimicrobial, cytotoxic and antioxidant effects of Naproxen metal complexes.
Md. Sharif Hasan, Narhari Das
doaj   +1 more source

Naproxen chemoprevention induces proliferation of cytotoxic lymphocytes in Lynch Syndrome colorectal mucosa

Frontiers in Immunology, 2023
BackgroundRecent clinical trial data from Lynch Syndrome (LS) carriers demonstrated that naproxen administered for 6-months is a safe primary chemoprevention that promotes activation of different resident immune cell types without increasing lymphoid ...
Charles M. Bowen, Nan Deng, Laura Reyes-Uribe, Edwin Roger Parra, Pedro Rocha, Luisa M. Solis, Ignacio I. Wistuba, Valerie O. Sepeda, Lana Vornik, Marjorie Perloff, Eva Szabo, Asad Umar, Krishna M. Sinha, Powel H. Brown, Eduardo Vilar, Eduardo Vilar   +15 more
doaj   +1 more source

Naproxen Exhibits Broad Anti-influenza Virus Activity in Mice by Impeding Viral Nucleoprotein Nuclear Export

Cell Reports, 2019
Summary: Naproxen is a non-steroidal anti-inflammatory drug that has previously been shown to exert antiviral activity against influenza A virus by inhibiting nucleoprotein (NP) binding to RNA.
Weinan Zheng, Wenhui Fan, Shuang Zhang, Pengtao Jiao, Yingli Shang, Liang Cui, Madina Mahesutihan, Jing Li, Dayan Wang, George Fu Gao, Lei Sun, Wenjun Liu   +11 more
doaj   +1 more source