Results 11 to 20 of about 133,497 (331)

Transferrin-Pep63-liposomes accelerate the clearance of Aβ and rescue impaired synaptic plasticity in early Alzheimer’s disease models

open access: yesCell Death Discovery, 2021
Alzheimer’s disease (AD) is characterized by aberrant accumulation of extracellular β-amyloid (Aβ) peptides in the brain. Soluble Aβ oligomers are thought to be the most neurotoxic species and are correlated with cognitive dysfunction in early AD ...
Xiu Yang   +13 more
doaj   +1 more source

Comparative study on main compounds and hypoglycemic effects of dispensing granules of Coptidis Rhizoma and Scutellaria–Coptis herb couple with traditional decoction

open access: yesChinese Medicine, 2023
Background The clinical applications of dispensing granules (DG) have increased dramatically. However, it is controversial whether the DG has the same quality and efficacy compared with traditional decoction (TD).
Huanhuan Yu   +7 more
doaj   +1 more source

The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia

open access: yesFrontiers in Molecular Neuroscience, 2022
It has been widely demonstrated by numerous preclinical studies and clinical trials that the neonates receiving repeated or long-time general anesthesia (GA) could develop prolonged cognitive dysfunction.
Lin-Hui Ma   +8 more
doaj   +1 more source

Rapid Qualitative and Quantitative Analysis of Morphine in the Street and Biological Samples Using Densitometry Scan of Thin Layer Chromatography [PDF]

open access: yesطب انتظامی, 2023
Aims: In recent years, research in the field of identifying and quickly determining the amount of narcotics, including morphine, has grown significantly.
Asghar Eftekhari   +2 more
doaj   +1 more source

Narcotics in Rheumatology [PDF]

open access: yesHealth Services Insights, 2013
Patients with rheumatic conditions often suffer from related chronic pain. When first-line traditional medications such as acetaminophen and anti-inflammatory medications do not suffice, then other options are needed. The traditional medications may ultimately not provide sufficient pain relief, or alternatively, they can pose as a contraindication ...
Mahsa Tehrani   +2 more
openaire   +3 more sources

Forensic Analysis of Fatal Heroin Overdose in Pakistan: Examination of Seized Materials and Postmortem Blood Sample [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology
Introduction: The concentration of heroin in street drugs is highly uncertain. This uncertainty of drug purity is the major cause of overdose. If it is used with a combination of other drugs, it can be fatal.
Muhammad Usman, Yawar Baig, Abid Naseer
doaj   +1 more source

Diagnostic capabilities of self-reported psychoactive substance use among patients admitted to psychiatric consultations in Benin, West Africa

open access: yesBMC Psychiatry, 2022
Background There is a high prevalence of psychoactive substance use among patients with mental health disorders. The optimal treatment of patients with mental health disorders requires an awareness of their history pertaining substance use.
Ahmat K. Abdelhakim   +5 more
doaj   +1 more source

Two parallel medial prefrontal cortex-amygdala pathways mediate memory deficits via glutamatergic projection in surgery mice

open access: yesCell Reports, 2023
Summary: The neural circuit mechanisms underlying postoperative cognitive dysfunction (POCD) remain elusive. We hypothesized that projections from the medial prefrontal cortex (mPFC) to the amygdala are involved in POCD.
Xiao-Yu Sun   +7 more
doaj   +1 more source

Health Facility Licensing Dispute

open access: yesUnnes Law Journal, 2020
Clinic is a health service facility that organizes individual health services that provide basic and/or specialist medical services. Primary Clinic (Klinik Pratama) is a Clinic that organizes basic medical services both general and specific. To establish
Delfina Gusman, Marryo Borry
doaj   +1 more source

Addressing the Global Tragedy of Needless Pain: Rethinking the United Nations Single Convention on Narcotic Drugs [PDF]

open access: yes, 2007
The lack of medical availability of effective pain medication is an enduring and expanding global health calamity. Despite important medical advances, pain remains severely under-treated worldwide, particularly in developing countries.
Allyn L. Taylor   +11 more
core   +2 more sources

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