Results 71 to 80 of about 74,644 (322)

Post‐Thyroidectomy Opioid Prescription and Risk of Persistent Opioid Use: A Propensity Matched Cohort Study

Head &Neck, EarlyView.
ABSTRACT Background This study evaluates the risk of persistent opioid use (POU) among thyroidectomy patients given postoperative opioids. Methods Patients undergoing thyroidectomy were identified using the TriNetX Research Platform (2010–2024). Cohorts were divided based on opioid prescriptions on the day of surgery.
Oluwatobiloba Ayo‐Ajibola, Milan P. Fehrenbach, Asher C. Park, Jonathan D. West, Daniel I. Kwon   +4 more
wiley   +1 more source

NAT10 inhibition alleviates astrocyte autophagy by impeding ac4C acetylation of Timp1 mRNA in ischemic stroke

Acta Pharmaceutica Sinica B
Although a single nucleotide polymorphism for N-acetyltransferase 10 (NAT10) has been identified in patients with early-onset stroke, the role of NAT10 in ischemic injury and the related underlying mechanisms remains elusive.
Li Yang, Xiaotong Li, Yaxuan Zhao, Hao Chen, Can Wang, Angrong Wu, Xintong Guo, Yue Huang, Qihui Wang, Lingyun Hao, Xiaowen Li, Ying Ji, Jin Ban, Guangtian Wang, Junli Cao, Zhiqiang Pan   +15 more
doaj   +1 more source

Unbearable Pain: India's Obligation to Ensure Palliative Care [PDF]

, 2009
This 102-page report found that many major cancer hospitals in India do not provide patients with morphine, despite the fact that more than 70 percent of their patients are incurable and likely to require pain treatment and palliative care.

core  

Effects of integrated programs for substance‐involved mothers on infant and child development outcomes: A systematic review and meta‐analysis

Infant Mental Health Journal: Infancy and Early Childhood, EarlyView.
Abstract Maternal substance use is a pressing public health issue that confers risk for maternal health, the parent‐infant relationship, and child development. Integrated interventions that jointly address maternal substance use and child development have shown promise for enhancing child outcomes.
Sophie Barriault, Mary Motz, Lamia Firasta, Hannah McDowell, Patrick R. Labelle, Nancy Poole, Nicole Racine   +6 more
wiley   +1 more source

Recent Utilization of Pediatric Extrapolation and Modeling and Simulation Approaches in Pediatric Drug Development in Japan

The Journal of Clinical Pharmacology, EarlyView.
Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima, Akihide Tsujimoto, Masako Saito, Jun Takeda, Makiko Natori, Satoshi Shoji   +5 more
wiley   +1 more source

Unemployed Black/African Americans With Disabilities’ Treatment Acquisition for Substance Use Disorder and Serious Mental Illness

Journal of Multicultural Counseling and Development, EarlyView.
ABSTRACT Black/African Americans with disabilities who live with substance use disorder and/or serious mental illness are an underserved population in mental health treatment. We conducted a quantitative analysis using the 2022 National Survey on Drug Use and Health (N = 317) to identify treatment trends and interpreted results using DisCrit and the ...
Jennifer M. Cook, Lee Za Ong, Melissa Deroche, ZeVida A. Jones, Kaela Schneider   +4 more
wiley   +1 more source

FEATURES OF STORAGE AND TRANSPORTATION OF NARCOTIC ANALGESICS IN CONDITIONS OF EMERGENCY SITUATIONS

Фармация и фармакология (Пятигорск), 2015
The article performs the analysis of the current state regulatory-legal framework relating to the use of narcotic analgesics in health care institutions in emergencies peace and wartime.There are developed recommendations for adapting the requirements ...
P. V. Oliynyk, B. P. Hromovyk
doaj   +1 more source

Apprehending narcotic smugglers in Malta [PDF]

, 1992
This is an account of the experience of the radiological department in identifying heroin smugglers coming from the African continent in transit through Malta.
Zammit, Anthony
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Immediate postoperative anesthesia with either lidocaine or bupivacaine: A short‐term clinical response

Journal of Periodontology, EarlyView.
Abstract Background The purpose of this randomized, three‐armed clinical trial is to determine if a postoperative injection of 0.5% bupivacaine is more effective than 2% lidocaine in controlling pain after periodontal flap surgery. Methods Seventy‐six patients planned for similar periodontal surgeries were included.
Jessica D. Koster, David E. Deas, Archontia Palaiologou, David J. Lasho, Anibal Diogenes   +4 more
wiley   +1 more source

Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors

Frontiers in Pharmacology
IntroductionThe paraventricular thalamic nucleus (PVT) is recognized for its critical role in pain regulation, yet the precise molecular mechanisms involved remain poorly understood. Here, we demonstrated an essential role of the microglial adenosine A2A
Yiping Cao, Yiping Cao, Yiping Cao, Zhou Wu, Zhou Wu, Zhou Wu, Moruo Zhang, Moruo Zhang, Moruo Zhang, Ran Ji, Ran Ji, Ran Ji, Hongxing Zhang, Hongxing Zhang, Hongxing Zhang, Lingzhen Song, Lingzhen Song, Lingzhen Song   +17 more
doaj   +1 more source