Results 91 to 100 of about 4,372,065 (283)

Anesthetic-mediated cardioprotection: from molecular mechanisms to clinical translation challenges

Frontiers in Physiology
Anesthetics have long been recognized as essential pharmacological agents for surgical procedures, primarily valued for their ability to induce unconsciousness and provide analgesia.
Tingting Fu, Xiao Jia, Can Tang, Dan Yu, Hui Zhou, Xinghe Wang, Xinghe Wang, Su Liu, Su Liu, Kunwei Wu, Kunwei Wu   +10 more
doaj   +1 more source

Barriers and facilitators to detoxification from opioid substitution treatment: A mixed‐methods systematic review

Addiction, EarlyView.
Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw, Suleyman Shah, India Olchefske, Louise M. Paterson, Mike J. Crawford, Anne Lingford‐Hughes   +5 more
wiley   +1 more source

Regulations on narcotic and psychotropic drugs assistance

, 2023
Introducere. Complexitatea problemelor ce țin de consumul stupefiantelor și psihotropelor necesită o atenție sporită din partea oricărui stat în ceea ce privește asigurarea legiferării stricte, dar reușite, a tuturor proceselor ce se referă la acest ...
Brumărel, Mihail, Buliga, Valentina, Adauji, Stela, Safta, Vladimir   +3 more
core  

Change of substance‐related hospitalisation in adolescents after cannabis legalisation in Thailand in 2022

Addiction, EarlyView.
Abstract Background and aims On 9 June 2022, Thailand changed its cannabis legislation, expanding access to individuals aged >18 years. Evidence suggests that such changes could increase the risk of cannabis use and related harms, and could influence patterns of use of other substances among adolescents.
Sirada Puetpaiboon, Songyos Rajborirug, Vorthunju Nakhonsri, Chumpol Ngamphiw, Peerapat Khunkham, Sissades Tongsima, Watcharapot Janpoung, Virasakdi Chongsuvivatwong   +7 more
wiley   +1 more source

Extract from the Report of the 38th Expert Committee on Drug Dependence, convened from 14 to 18 November 2016, at WHO headquarters in Geneva.

, 2016
Agenda item 6 (b) Implementation of the international drug control treaties: changes in the scope of control of substances. Extract from the Report of the 38th Expert Committee on Drug Dependence: Substances recommended to be scheduled in Schedule I

core  

Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors

Frontiers in Pharmacology
IntroductionThe paraventricular thalamic nucleus (PVT) is recognized for its critical role in pain regulation, yet the precise molecular mechanisms involved remain poorly understood. Here, we demonstrated an essential role of the microglial adenosine A2A
Yiping Cao, Yiping Cao, Yiping Cao, Zhou Wu, Zhou Wu, Zhou Wu, Moruo Zhang, Moruo Zhang, Moruo Zhang, Ran Ji, Ran Ji, Ran Ji, Hongxing Zhang, Hongxing Zhang, Hongxing Zhang, Lingzhen Song, Lingzhen Song, Lingzhen Song   +17 more
doaj   +1 more source

Fifty-sixth session of the Commission on Narcotic Drugs opens in Vienna.

, 2013
11 March 2013 - The Fifty-sixth session of the Commission on Narcotic Drugs (CND) kicks off today with over 1,000 representatives from Member States and civil society, as well as high level speakers and government ministers from across the globe.

core  

Unauthorized possession of narcotic drugs : (international standards and law of the Republic of Serbia) [PDF]

На бази универзалних, односно регионалних међу- народних стандарда бројна кривична законодавства, па тако и позитивно законодавство Републике Србије познаје више кривич- них дела злоупотребе опојних дрога.
Jovašević, Dragan
core   +1 more source

Lysosomes finely control macrophage inflammatory function via regulating the release of lysosomal Fe2+ through TRPML1 channel

Nature Communications
Lysosomes are best known for their roles in inflammatory responses by engaging in autophagy to remove inflammasomes. Here, we describe an unrecognized role for the lysosome, showing that it finely controls macrophage inflammatory function by manipulating
Yanhong Xing, Meng-meng Wang, Feifei Zhang, Tianli Xin, Xinyan Wang, Rong Chen, Zhongheng Sui, Yawei Dong, Dongxue Xu, Xingyu Qian, Qixia Lu, Qingqing Li, Weijie Cai, Meiqin Hu, Yuqing Wang, Jun-li Cao, Derong Cui, Jiansong Qi, Wuyang Wang   +18 more
doaj   +1 more source

Legalisation and decriminalisation of narcotic drugs and psychotropic substances [PDF]

, 2023

core   +1 more source