Results 231 to 240 of about 502,900 (314)

Methylation‐Induced Permanent Charge Polarization in Covalent Organic Frameworks for Visible Light‐Driven Water Decontamination and Disinfection

open access: yesAdvanced Science, EarlyView.
A targeted in situ methylation strategy is developed to engineer cationic centers in a quinoline‐linked COF (NQ‐COFS1‐Me), creating a strong built‐in electric field, which effectively suppresses excitonic effects and promotes charge separation. The optimized material demonstrates powerful photocatalytic ROS generation for rapid bacterial inactivation ...
Xuewen Peng   +7 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

Sentiment analysis of research attention: the Altmetric proof of concept. [PDF]

open access: yesFront Res Metr Anal
Areia C   +3 more
europepmc   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu   +15 more
wiley   +1 more source

Hostility in the ICU Waiting Room: Extrapunitive and Intropunitive Reactions Among Family Members. [PDF]

open access: yesHealthcare (Basel)
Konstanti Z   +6 more
europepmc   +1 more source

Selective Confinement by a COF‐Derived Sub‐Nanoporous Interface for High‐Performance CoF2 Thermal Battery Cathodes

open access: yesAdvanced Science, EarlyView.
Dissolution and shuttling of TMF cathodes hinders high‐voltage thermal batteries. A novel selective confinement strategy using a sub‐nanoporous COF‐derived carbon interface (0.54 nm pores) on CoF2 suppresses cathode material shuttling. Size‐selective confinement blocks large dissolved ions (∼0.8 nm) while allowing Li⁺ passage, enhancing thermal battery
Mengfan Xu   +9 more
wiley   +1 more source

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

open access: yesAdvanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan   +8 more
wiley   +1 more source

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