British Journal of Clinical Pharmacology, EarlyView.Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott +16 more
wiley +1 more source
From battlefield to living room: a community-based narrative intervention for reciprocal healing during war. [PDF]
Front Public HealthCohen Zada O.
europepmc +1 more source
Regulatory harmonization: Evolution, globalization and future directions
British Journal of Clinical Pharmacology, EarlyView.Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies +2 more
wiley +1 more source
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications
British Journal of Clinical Pharmacology, EarlyView.Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba +2 more
wiley +1 more source
A double narrative: stories underpin fearful community attitudes toward snakes but offer a mechanism to reduce human-to-snake conflict. [PDF]
Glob Health ActionMeirinho Domingues D +4 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed +7 more
wiley +1 more source
Addressing the complexity of recovery beyond reductionist, diagnosis‑driven care: a realist evaluation of a family-centered, narrative-based child and adolescent psychiatry practice. [PDF]
BMC PsychiatryGodthelp J +6 more
europepmc +1 more source
'I Put a Lot of Emotion in My Work, I Use It, It's My Tool': An Ethnographic Account of Algorithmic Homecare Assistance in the Netherlands. [PDF]
Sociol Health IllnBergamin E, Wallenburg I.
europepmc +1 more source
Helpers' stories of providing support to bereaved individuals following drug-related death: a narrative study. [PDF]
Int J Qual Stud Health Well-beingKristiansen C, Samsonsen V, Lindeman SK.
europepmc +1 more source