Results 111 to 120 of about 665,368 (284)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Expanding Narrative Medicine: Four Notes

Canadian Journal of Bioethics
Considering the possible futures of bioethics invites us to interrogate our existing theories and methods. This text focuses on futures for narrative medicine, offering four notes for an expanded practice.
C Dalrymple-Fraser
doaj   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Beyond the bedside: Re-imagining narrative medicine for knowledge translation

Encounters in Translation
This article challenges the conventional dichotomy between narrative medicine and translational medicine, arguing that they are not opposites but mutually interdependent frameworks within medical research and practice.
Eivind Engebretsen
doaj   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Narrative Thinking of Healthcare Providers in Medical Cases and Its Implications for Modern Medical Education

Chinese Medicine and Culture
. In the realm of Chinese narrative medicine, narrative thinking holds equal significance to evidence-based thinking within clinical practice, making substantial contributions to patient safety and medical quality.
Xiaolin YANG, Qing HUANG, Zhiheng GUO
doaj   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Sea Urchin‐Inspired Immuno‐Instructive Ionic Flow Drives MSCs‐Macrophage Communication to Promote Bone Regeneration

Advanced Materials, EarlyView.
ABSTRACT Bone tissue regeneration is a complex physiological process dependent on the spatiotemporal coordination of immune cells and stem cells. Conventional research primarily elucidates the mechanism through which materials facilitate bone formation by initially modulating macrophages and subsequently encouraging the osteogenic differentiation of ...
Yang Lu, Kun Su, Daqian Liu, Chunyu Liu, Muyan Qin, Shuaijie Li, Pengfei Tian, Yansong Wang, Yingbo Wang, Lei Chu, Xu Cui, Haobo Pan   +11 more
wiley   +1 more source

The Narrative Medicine Practice for the Treatment of Ben Tun Qi

Chinese Medicine and Culture
. This article takes the narrative medicine practice of traditional Chinese medicine (TCM) in the treatment of Ben Tun Qi (奔豚气) as an example to illustrate the characteristics of narrative medicine in TCM diagnosis and treatment, and strives to form a ...
Zixu WANG, Yipin LIU, Jin LU
doaj   +1 more source

Electronic Structure Modulation Induced by Asymmetric Cu─Ni Centers in a π‐Conjugated Triazine MOF

Advanced Materials Interfaces, EarlyView.
A π‐conjugated H3TATB‐based asymmetric bimetallic CuNi‐MOF was developed as an efficient electrocatalyst for alkaline hydrogen evolution. Benefiting from synergistic Cu–Ni interactions, enhanced charge transfer, and stabilized active sites, CuNi‐MOF delivers superior HER performance with low overpotential, improved kinetics, and 24 h durability.
Alamgir, Raza Ullah, Nouraiz Mushtaq, Agasthiyaraj Lakshmanan, Abrar Ahmad, Xusheng Wang, Junbo Liang, Sailing He   +7 more
wiley   +1 more source