Results 61 to 70 of about 2,438,339 (329)

Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Tuberculosis (TB), a contagious disease caused by Mycobacterium tuberculosis                          (M. tuberculosis), remains a health problem worldwide and this infection has the highest mortality rate among bacterial infections ...
Arshid Yousefi Avarvand, Zahra Meshkat, farzad khademi, Ehsan Aryan, Mojtaba Sankian, Mohsen Tafaghodi   +5 more
doaj   +1 more source

Frovatriptan succinate intranasal delivery for brain targeting – in vivo study.‎

The Iraqi Journal of Veterinary Medicine, 2023
Muco-adhesive gel formulations are advantageous in extending the stay at the nasal ‎absorption place, promoting drug absorption. Frovatriptan succinate (FVT) exhibits a 35% ‎oral bioavailability and undergoes hepatic metabolism, making it a viable ...
Mohammed layth hamzah, Hanan Jalal Kassab   +1 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Intranasal preoperative sedation with sufentanil in children

Медицина неотложных состояний
Background. Preoperative anxiety in children is a significant issue that negatively affects both their psycho-emotional state and surgical outcomes. Children aged 3–8 years often experience fear of separation from parents, of medical procedures, and drug
В.І. Коломаченко, І.Ю. Одинець, О.Є. Гавриков, В.І. Купін   +3 more
doaj   +1 more source

Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases [PDF]

, 2017
Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials.
Allen, Angus, Bannasch, Barrs, Beatty, Bennett, Berryessa, Bexfield, Binns, Bongrand, Boothe, Bradley, Burns, Chalker, Chalker, Chan, Chandler, Confalonieri, Danish Small Animal Veterinary Association (SvHKS), Dear, Demetriou, Demko, Dossin, Drawz, Egberink, Ellis, Erles, German, Guardabassi, Hartmann, Helps, Henderson, Hollis, Hunter, Jameson, Johnson, Johnson, Johnson, Johnson, Johnson, Keil, Kogan, Kompare, Lee, Lees, Levy, Lionel, Litster, MacPhail, Maggs, Martino, McInnis, McKiernan, Meijvis, Melendez, Meyers, Mochizuki, Morley, Mulholland, Murphy, Owen, Papich, Parnham, Peeters, Pesavento, Priestnall, Priestnall, Proulx, Pui-Ying, Quimby, Quimby, Radhakrishnan, Renshaw, Rheinwald, Rheinwald, Rooney, Rozanski, Ruch-Galle, Ruch-Gallie, Ruch-Gallie, Schulz, Schwarz, Sparkes, Speakman, Speakman, Spindel, Stillion, Sturgess, Sykes, Tart, Trow, Tynan, Vanderkooi, Veir, Velineni, Viitanen, Waddell, Walker, Welsh, Westfall, Wong, Zhu   +101 more
core   +4 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe, Bernard, Julie, Bernex, Florence, Castagné, Nathalie, Deplanche, Martine, Deville, Sébastien, Dubosclard, Virginie, Dubuquoy, Catherine, Durand, Guillaume, Eléouët, Jean-François, Meyer, Gilles, Petit-Camurdan, Agnès, Riffault, Sabine, Schwartz-Cornil, Isabelle, Soulestin, Marion   +14 more
core   +2 more sources

Lactobacillus rhamnosus CRL1505 nasal administration improves recovery of T-cell mediated immunity against pneumococcal infection in malnourished mice.

Beneficial Microbes, 2017
Immunobiotic lactic acid bacteria have become an interesting alternative for the prevention of respiratory infections. Previously, we demonstrated that the nasal administration of Lactobacillus rhamnosus CRL1505, during repletion of malnourished mice ...
N. Barbieri, M. Herrera, S. Salva, J. Villena, S. Alvarez   +4 more
semanticscholar   +1 more source

Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung, Florentin Steigerwald, Amy Romanello, Cathrin Kodde, Matthias Endres, Sandra Frank, Peter Heuschmann, Philipp Koehler, Stephan Krohn, Daniel Pape, Jens Schaller, Sophia Stöcklein, Istvan Vadasz, Janne Vehreschild, Martin Witzenrath, Thomas Zoller, Carsten Finke, on behalf of the NAPKON Study Group, Y. Ahlgrimm, C. Finke, J. Fricke, T. Keil, L. Krist, N. Lisewsky, M. Mittermaier, M. Mueller‐Plathe, C. Pley, S. Schmidt, A. Stege, F. Steinbeis, S. Steinbrecher, C. Wildberg, M. Witzenrath, E. Zessin, T. Zoller, C. Arendt, C. Bellinghausen, S. Cremer, A. Groh, A. Gruenewaldt, Y. Khodamoradi, S. Klinsing, G. Rohde, M. Vehreschild, T. Vogl, S. Frank, J. C. Hellmuth, M. Huber, S. Kaeaeb, O. T. Keppler, E. Khatamzas, C. Mandel, S. Mueller, M. Muenchhoff, L. Reeh, C. Scherer, H. Stubbe, M. von Bergwelt, L. Weiss, B. Zwissler, S. Cleef, M. E. Figuera Basso, J. Franzenburg, K. Franzpoetter, A. Friedrichs, A. Hermes, J. Heyckendorf, C. Kujat, I. Lehmann, C. Maetzler, S. Meier, D. Pape, S. Poick, L. Reinke, A. K. Russ, A. M. Scheer, D. Schunk, T. Tamminga, S. Bohnet, D. Droemann, K. F. Franzen, R. Hoerster, N. Kaeding, M. Nissen, P. Parschke, J. Rupp, S. Caesar, H. Einsele, S. Frantz, A. Frey, A. Grau, K. Haas, C. Haertel, K. G. Haeusler, G. Hein, J. Herrmann, A. Horn, R. Jahns, P. Meybohm, F. A. Montellano, C. Morbach, J. Schmidt, P. Schulze, S. Stoerk, J. Volkmann, T. Bahmer, A. Hermes, M. Krawczak, W. Lieb, S. Schreiber, T. Tamminga, B. Balzuweit, S. Berger, J. Fricke, M. Hummel, A. Krannich, L. Krist, F. Kurth, J. Lienau, R. Lorbeer, C. Pley, J. Schaller, S. Schmidt, C. Thibeault, M. Witzenrath, T. Zoller, I. Bernemann, T. Illig, M. Kersting, N. Klopp, V. Kopfnagel, S. Muecke, M. Kraus, B. Lorenz‐Depiereux, G. Anton, A. Kuehn‐Steven, S. Kunze, M. K. Tauchert, K. Appel, M. Brechtel, I. Broehl, K. Fiedler, R. Geisler, S. M. Hopff, K. Knaub, C. Lee, S. Nunes de Miranda, S. Raquib, G. Sauer, M. Scherer, J. J. Vehreschild, P. Wagner, L. Wolf, J. C. Hellmuth, K. Guenther, F. Haug, J. Haug, A. Horn, M. Kohls, C. Fiessler, P. U. Heuschmann, O. Miljukov, C. Nuernberger, J. P. Reese, L. Schmidbauer, I. Chaplinskaya, S. Hanss, D. Krefting, C. Pape, M. Rainers, A. Schoneberg, N. Weinert, T. Bahls, W. Hoffmann, M. Nauck, C. Schaefer, M. Schattschneider, D. Stahl, H. Valentin, P. Heuschmann, A. L. Hofmann, S. Jiru‐Hillmann, J. P. Reese, S. Herold, P. Heuschmann, R. Heyder, W. Hoffmann, T. Illig, S. Schreiber, J. J. Vehreschild, M. Witzenrath   +190 more
wiley   +1 more source

In vivo nose-to-brain delivery of the hydrophilic antiviral ribavirin by microparticle agglomerates

Drug Delivery, 2018
Nasal administration has been proposed as a potential approach for the delivery of drugs to the central nervous system. Ribavirin (RBV), an antiviral drug potentially useful to treat viral infections both in humans and animals, has been previously ...
Alessandro Giuliani, Anna Giulia Balducci, Elisa Zironi, Gaia Colombo, Fabrizio Bortolotti, Luca Lorenzini, Viola Galligioni, Giampiero Pagliuca, Alessandra Scagliarini, Laura Calzà, Fabio Sonvico   +10 more
doaj   +1 more source