Results 161 to 170 of about 6,988 (249)

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

open access: yesEpilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer   +7 more
wiley   +1 more source

Pathological hippocampal–cortical hypersynchronization disrupts memory in temporal lobe epilepsy: A multimodal intracranial electroencephalographic–functional magnetic resonance imaging study

open access: yesEpilepsia, EarlyView.
Abstract Objective Memory impairment is a common comorbidity in temporal lobe epilepsy (TLE) and is thought to arise from hippocampal dysfunction and disrupted interactions within a distributed memory network involving medial temporal, frontal, and parietal cortical regions.
Ruxue Gong   +8 more
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Selecting Between Hydrogen and Methanol for Fuel Cell‐Organic Rankine Cycle Hybrid Power Systems: A Comparative 4E Analysis

open access: yesEnergy Science &Engineering, EarlyView.
A 4E comparison of PEMFC‐ORC and DMFC‐ORC systems shows that PEMFC‐ORC achieves 21% higher energy efficiency, while DMFC‐ORC obtains 31% higher exergy efficiency and 57% lower levelized cost of electricity. However, DMFC‐ORC emits nearly twice the annual carbon dioxide equivalent of PEMFC‐ORC.
Zahra Piryaei   +2 more
wiley   +1 more source

Techno‐Economic Analysis and Multi‐Objective Optimization of a Novel Combined Cooling and Power System Driven by Geothermal Source and Waste Heat From Data Center

open access: yesEnergy Science &Engineering, EarlyView.
A novel combined cooling and power generation system is proposed by integrating organic Rankine cycle (ORC) with an absorption heat transformer, which is driven by combining geothermal energy and data center's waste heat. The system using R601a yielded the best overall performance, achieving an exergy efficiency of 40.34% and an annual cost of 130.29 k$
Zerui Chen   +4 more
wiley   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee   +4 more
wiley   +1 more source

A study of the forces generated during equine cheek tooth extraction

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Significant force is often applied when elevating equine teeth from the alveolus during extraction. No previous studies have investigated these forces. Objectives To develop a method to allow measurement of elevation forces (EF) applied during extraction, and to record forces during extraction of cheek teeth in both cadaver ...
Tom N. A. McGinley   +1 more
wiley   +1 more source

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